Results 171 to 180 of about 508,484 (293)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Novel Zwitterionic Polydopamine Nanofiller‐Reinforced Hybrid Membranes With Superior Antifouling Performance for Wastewater Treatment

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work reports one‐pot synthesized novel zwitterionic polydopamine‐silica (ZSiPDA) nanofillers for fabricating PES hybrid ultrafiltration membranes with enhanced hydrophilicity, permeability, and antifouling performance. The optimized membrane achieved over 91% humic acid removal and showed strong potential for municipal wastewater treatment.
Roqaya A. Ismail   +5 more
wiley   +1 more source

Glucagon-like peptide-1 receptor signaling deficiency exacerbates hematopoietic stem cell graft rejection in mice. [PDF]

open access: yesJ Immunol
Rusznak M   +17 more
europepmc   +1 more source

Chemically Modular, Nonfluorinated Polymer Adsorbents for Capturing Per‐ and Polyfluoroalkyl Substances (PFAS)

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Nonfluorinated polymer networks for PFAS adsorption are synthesized using active ester click chemistry. Incorporating Lewis base ligands along with hydrophilic and hydrophobic co‐monomers leads to high PFOA binding efficiency. Ligand basicity and pH are found to play an important role in PFOA sorption.
Lakshay K. Dhamania, Joshua D. Moon
wiley   +1 more source

“We Are Willing to Change, If…”: Potential Impacts of Citizens' Assemblies on the Willingness to Change for Sustainability in Rural East German Municipalities

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT In light of the democratic and social‐ecological crises, deliberative minipublics such as citizens' assemblies are increasingly implemented and discussed by scholars as a means for sound decision‐making and to enhance public support for sustainability transformations.
Lea Findeis, Nicolas Jager
wiley   +1 more source

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