Results 21 to 30 of about 8,034,026 (305)

Treatments and supportive therapies for oral manifestations of chronic graft-versus-host disease

open access: yesActa Scientiarum. Health Sciences, 2016
The aim of this study was to conduct a systematic review of treatments and therapies for oral manifestations of chronic graft-versus-host disease, aiming at improving patients’ quality of life and mainly the reduction of mortality caused by graft-versus-
Rafaella Gabriel Maiolino   +5 more
doaj   +1 more source

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study [PDF]

open access: yes, 2019
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. First-line treatment is based on the use of high doses of corticosteroids.
González Vicent, Marta   +109 more
core   +3 more sources

Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease

open access: yesHaematologica, 2015
Effective pharmacological strategies employed in allogeneic hematopoietic cell transplantation should prevent serious chronic graft-versus-host disease and facilitate donor-recipient immune tolerance.
Joseph Pidala   +15 more
doaj   +1 more source

Donor characteristics and hematopoietic stem cell transplantation outcome: experience of a single center in Southern Brazil

open access: yesHematology, Transfusion and Cell Therapy, 2018
Background: Hematopoietic stem cell transplantation is a curative treatment for many patients with hematological disorders. Donor–recipient genetic disparity, especially involving the human leukocyte antigen system is a critical factor for transplant ...
Alessandra Paz   +12 more
doaj   +1 more source

Bendamustine Conditioning Skews Murine Host DCs Toward Pre-cDC1s and Reduces GvHD Independently of Batf3

open access: yesFrontiers in Immunology, 2020
Graft-versus-host disease (GvHD) remains the second leading cause of death in allogeneic hematopoietic stem cell transplantation recipients, highlighting the need for improved preventative strategies.
Megan S. Molina   +14 more
doaj   +1 more source

Transfusion-associated graft-vs-host disease – A case report [PDF]

open access: yes, 2016
Transfusion-associated graft-vs-host disease (TAGVHD) is a rare complication of blood transfusion. Unlike GVHD associated with hematopoietic stem cell transplantation TA-GVHD involves the patient's bone marrow and leads to bone marrow aplasia.
Bhattacharyya, Jina; Department of Clinical Hematology, Gauhati Medical College, Guwahati, India   +5 more
core   +1 more source

Severe acute graft versus host disease after lung transplant: report of a case successfully treated with high dose corticosteroids

open access: yes, 2009
Acute graft vs host disease is an uncommon and usually fatal complication of lung transplant for which no effective therapy exists. All 8 patients with grade 3 to 4 acute graft vs host disease after lung transplantation described in literature died ...
LAGHI PASINI F.   +16 more
core   +2 more sources

Treatment of Severe Steroid-Refractory Acute-Graft-vs.-Host Disease With Mesenchymal Stem Cells–Single Center Experience [PDF]

open access: yes, 2018
The most effective treatment of steroid refractory acute graft vs. host disease (aGvHD) is not yet established and mesenchymal stem cells (MSC) appear to be a promising therapy for the condition. We report single center case series of three patients, who
Miomir Kneževič   +4 more
core   +1 more source

Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graft-versus-host disease [PDF]

open access: yes, 2010
Background Multipotent mesenchymal stromal cells suppress T-cell function in vitro, a property that has underpinned their use in treating clinical steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation ...
K. Atkinson   +19 more
core   +1 more source

Consensus on graft-versus-host disease

open access: yesJournal of Bone Marrow Transplantation and Cellular Therapy
Graft-versus-host disease (GvHD) remains the mainly cause of late non-relapse mortality following allogeneic hematopoietic cell transplantation. Advancements in novel immunosuppressive therapies and prophylactic regimens necessitate an update to current ...
Vaneuza Araújo Moreira Funke   +10 more
doaj   +1 more source

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