Results 21 to 30 of about 160,953 (345)
Frontiers in Bioengineering and Biotechnology, 2018 The most effective treatment of steroid refractory acute graft vs. host disease (aGvHD) is not yet established and mesenchymal stem cells (MSC) appear to be a promising therapy for the condition. We report single center case series of three patients, who
Maja Česen Mazič +4 more
doaj +2 more sources
Toll-Like Receptor Stimulation by MicroRNAs in Acute Graft-vs.-Host Disease
Frontiers in Immunology, 2018 Acute graft-vs.-host disease (aGVHD) is a frequent complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), accounting for substantial morbidity and mortality associated with this treatment modality.
Nina C. Zitzer +3 more
doaj +2 more sources
Review of Cutaneous Graft-vs-Host Disease
Actas Dermo-Sifiliográficas (English Edition), 2016 Graft-vs-host disease (GVHD) is a multisystem disease that arises as a complication of allogeneic hematopoietic stem cell transplant. It is due to recognition of the recipient's tissues by immune cells from the donor. The skin and mucous membranes are the organs most commonly affected.
Ballester-Sánchez R +3 more
openaire +4 more sources
JAMA Network Open, 2021 Key Points Question Is ruxolitinib an option for patients with steroid-refractory chronic graft-vs-host disease, and what characteristics are associated with treatment response?
Hengwei Wu +10 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Histone deacetylase inhibitors are currently the most studied drugs because of their beneficial effects on inflammatory response. Emerging data from numerous basic studies and clinical trials have shown that histone deacetylase inhibitors can suppress ...
Xiaoxiao Xu +3 more
semanticscholar +1 more source
Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD
Biology, 2023 Graft-versus-host disease (GVHD) is a life-threatening systemic complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by dysregulation of T and B cell activation and function, scleroderma-like features, and multi-organ ...
Deepika Raman +7 more
doaj +1 more source
Dermatology Online Journal, 2013 We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented ...
Tran, Kathleen +3 more
openaire +4 more sources
Role of HRCT Chest in Post Stem Cell Transplant Recipients Suspected of Pulmonary Complications [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Stem cell transplantation is today’s procedure of choice for management of various hematopoietic malignant and severe immunogenic disorders. High Resolution Computed Tomography (HRCT) is a common technique for the diagnosis of pulmonary
Abhishek Dwivedi +3 more
doaj +1 more source
Journal of Clinical Investigation, 2021 Inhibitors of calcineurin phosphatase activity (CNIs) such as cyclosporin A (CsA) are widely used to treat tissue transplant rejection and acute graft-versus-host disease (aGVHD), for which inhibition of NFAT-dependent gene expression is the mechanistic ...
S. Otsuka +5 more
semanticscholar +1 more source
Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review [PDF]
Annals of Coloproctology, 2020 Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition.
Kwang-Seop Song +9 more
doaj +1 more source