Results 221 to 230 of about 7,425,086 (301)

Global Multidisciplinary Variation in Idiopathic Subglottic Stenosis Surgical Management

The Laryngoscope, EarlyView.
This international cross‐sectional survey of 193 clinicians across 42 countries reveals substantial global and multidisciplinary variation in the surgical management of idiopathic subglottic stenosis (iSGS). While endoscopic dilation remains near‐universally utilized, practice patterns differ significantly regarding technical execution, adjuvant ...
Emilie A. C. Dronkers, Jip Y. Mulders, Dale Ekbom, Alexander Gelbard, Karla O'Dell, Ricky Thakrar, Ad Verhagen, Chadwan Al Yaghchi   +7 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Editorial: Advances in ocular surface disease

Frontiers in Medicine
Hong Qi, Hong Qi, Jin Yuan, Kyung Chul Yoon, Hong Liang, Hong Liang   +5 more
doaj   +1 more source

Longitudinal Tear Cytokine Biomarkers: An Analysis from the Close Assessment and Testing for Chronic Graft-Versus-Host Disease (CATCH) Protocol. [PDF]

Transplant Cell Ther
El Jurdi N, Hamilton BK, Pidala JA, Onstad L, Mun C, Jain S, Lee SJ.   +6 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

Risk of Subsequent Vitiligo in Transplant Recipients With Comorbid Graft-vs-Host Disease.

JAMA Dermatol
Bang CH, Park HE, Kim YH, Jung JH, Lee JH, Park YM, Han JH.   +6 more
europepmc   +1 more source