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Graft-vs-Host Disease

2000
The transplantation of healthy hematopoietic stem cells into a patient with aplastic anemia or leukemia is potentially curative therapy, but the development of acute graftvs-host disease (GVHD), which often occurs even when the donor and recipient are siblings fully matched at the human leukocyte antigen (HLA) loci, significantly limits survival.The ...
Thomas R. Spitzer, Robert Sackstein
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Graft-vs-host disease

Bone Marrow Transplantation, 2005
JLM Ferrara, KR Cooke and HJ Deeg (eds) Third edition, 2005. Marcel Dekker, New York, NY, USA, ISBN: 0-8247-5472-7, 645pp.
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Ocular Manifestations of Graft-vs-Host Disease

Ophthalmology, 1983
In patients who have graft-vs-host disease (GVHD) after bone marrow transplantation, ocular involvement occurs in approximately 60% of cases. Among 13 such GVHD patients, the most frequent ocular manifestations included keratoconjunctivitis sicca, cicatricial lagophthalmos, and sterile conjunctivitis and uveitis.
R M, Franklin   +5 more
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Life-threatening graft-vs-host disease

Clinics in Dermatology, 2005
Hematopoietic stem cell transplant (SCT) is considered standard therapy for a variety of malignant and nonmalignant diseases. Graft-versus-host disease (GVHD) still represents today a major complication of hematopoietic SCT. Two types of GVHD have traditionally been recognized on the basis of the time of onset following transplantation, distinct ...
Erich, Vargas-Díez   +3 more
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Graft vs. Host Disease

2004
Transplantation immunobiology: thymic T-cell development MHC class 1: structure and function MHC class II: structure and function biological inhibitors of lymphocyte coreceptors for antigen-specific immunosuppression immunosuppression andimmunophilin ligands: cyclosporin A, FK506, and rapamycin leucocyte adhesion, trafficking, and migration cytokine ...
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Blood Transfusions and Graft-vs-Host Disease

Archives of Dermatology, 1990
Decoste et al 1 report on transfusion-associated graft-vs-host disease (GVHD) in this issue of theArchivesand raise important considerations for dermatologists evaluating morbilliform erythemas and exanthems. In healthy individuals, such eruptions are frequently attributed (correctly or otherwise) to a drug sensitivity or reaction, often on criteria of
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[Graft vs host disease].

Pathologie-biologie, 2006
Graft vs host disease is a serious immunological complication of allogeneic haematopoietic cell transplantation, leading to a significant morbidity and mortality. It occurs when donor T lymphocyte react to foreign host cells. The physiopathology is a more complex process implicating host tissues damage caused by the conditioning regimen, cytokines ...
V, Moalic, C, Ferec
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Antigen presentation in graft-vs-host disease

Experimental Hematology, 2003
Graft-vs-host disease (GVHD) and the sequela of immunosuppression used to prevent it remain major causes of morbidity and mortality in allogeneic stem cell transplantation (alloSCT). In particular, GVHD and ineffective T-cell immune reconstitution significantly decreases the enthusiasm for offering alloSCT to patients with non-malignant inherited ...
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Acute Graft-vs-Host Disease

Archives of Dermatology, 1987
• Graft-vs-host disease (GVHD) is a frequent complication of allogeneic bone marrow transplantation but has been infrequently reported following autologous or syngeneic bone marrow transplantation. Ninety-six autologous and 19 syngeneic marrow transplants were performed at our institution between July 1977 and March 1984. We report acute cutaneous GVHD
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Photopheresis in graft‐vs.‐host disease

ISBT Science Series, 2007
Keywords: Extracorporeal photopheresis (ECP); Graft versus host disease (GvHD); Haematopoietic stem cell transplantation (HSCT)
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