A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Assessment of the Potential of Bitter Melon (<i>Momordica charantia</i>) and Squash (<i>Cucurbita pepo</i>) as Rootstocks for Enhancing Drought Tolerance in Cucumber. [PDF]
Kacar A +6 more
europepmc +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Salinity strengthens plant-pollinator mutualism through leaf physiological status in grafted tomatoes. [PDF]
Prudencio ÁS +7 more
europepmc +1 more source
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen +17 more
wiley +1 more source
Scion-based drought stress memory affects potato response to water deficit. [PDF]
Marczewski W +5 more
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Synergistic effects of grafting and companion cropping reshape the root endophytic microbiome network to regulate yield and fruit quality in continuously monocropped watermelon. [PDF]
Kang L +10 more
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Metabolomic and transcriptomic analyses reveal grafting-regulated nutritional and flavor metabolites in tomato. [PDF]
Ma Y +5 more
europepmc +1 more source

