Results 51 to 60 of about 48,438 (297)

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

A comparative study among different methods of detection of colistin resistant gram negative bacilli in a tertiary care hospital

Journal of Medical and Scientific Research, 2020
Background: Multi-drug resistant gram negative bacteria (MDR GNB) have become a major health challenge worldwide. Colistin has an excellent bactericidal activity against these MDR GNB. However, Colistin resistance has been reported globally.
Poonam AR, Bilolikar AK, Sahu S
doaj   +1 more source

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

Plants, plant‐derived compounds, probiotics, and postbiotics as green agents to fight against poultry coccidiosis: A review

Animal Research and One Health, EarlyView.
Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen, Kaili Liu, Taojing Yue, Yanan Lu, Senyang Li, Fuchun Jian, Shucheng Huang   +6 more
wiley   +1 more source

OCULAR INFECTIONS: RATIONAL APPROACH TO ANTIBIOTIC THERAPY

National Journal of Medical Research, 2012
Background: Isolation of common pathogens involved in ocular infection and their in-vitro susceptibility to commonly used ocular antibiotics, as well as the trends in antibiotic resistance developed by these pathogens were investigated.
Mulla Summaiya A, Khokhar Neeta D, Revdiwala Sangita B   +2 more
doaj  

Global Spread of Multiple Aminoglycoside Resistance Genes

Emerging Infectious Diseases, 2005
Emergence of the newly identified 16S rRNA methylases RmtA, RmtB, and ArmA in pathogenic gram-negative bacilli has been a growing concern. ArmA, which had been identified exclusively in Europe, was also found in several gram-negative pathogenic bacilli ...
Kunikazu Yamane, Jun-ichi Wachino, Yohei Doi, Hiroshi Kurokawa, Yoshichika Arakawa   +4 more
doaj   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

BMEMat, EarlyView.
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian, Huijun Ye, Pan Wang, Changxing Li, Xutao Guo, Ming Guan, Shilun Feng   +6 more
wiley   +1 more source

Distribution of Aerobic Intestinal Microorganisms in the Feces of the Striped Field Mouse (Apodemus agrarius coreae) in Jeju

Korean Journal of Clinical Laboratory Science
This study examined the fecal samples of striped field mice (Apodemus agrarius coreae) captured in Jeju Special Self-Governing Province. Fecal samples, including the colon and other intestinal organs, were collected and subjected to aerobic culture to ...
Jiro KIM, Yun-Hee OH, Moo-Sang CHONG
doaj   +1 more source