Results 81 to 90 of about 48,438 (297)

Efficient and Accurate Tuberculosis Diagnosis: Attention Residual U-Net and Vision Transformer Based Detection Framework [PDF]

arXiv
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, continues to be a major global health threat despite being preventable and curable. This burden is particularly high in low and middle income countries. Microscopy remains essential for diagnosing TB by enabling direct visualization of Mycobacterium tuberculosis in sputum ...
arxiv  

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

Cytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar, Joyeeta Chakraborty, Pananghat Gayathri, Ramanujam Srinivasan   +3 more
wiley   +1 more source

AmpC and extended spectrum beta-lactamases production among urinary isolates from a tertiary care hospital in Lalitpur, Nepal

BMC Research Notes, 2017
Background Production of AmpC and extended spectrum beta-lactamases among urinary isolates has created a serious problem to the successful management of the urinary tract infection.
Suman Rai, Narayan Dutt Pant, Raju Bhandari, Anil Giri, Roshan Parajuli, Manoj Aryal, Jyoti Amatya, Vijay Kumar Sharma   +7 more
doaj   +1 more source

MORPHOLOGICAL CHANGES IN GRAM-NEGATIVE BACILLI EXPOSED TO CEPHALOTHIN [PDF]

, 1964
Te‐Wen Chang, Louis Weinstein
openalex   +1 more source

Enhanced Tuberculosis Bacilli Detection using Attention-Residual U-Net and Ensemble Classification [PDF]

arXiv
Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a critical global health issue, necessitating timely diagnosis and treatment. Current methods for detecting tuberculosis bacilli from bright field microscopic sputum smear images suffer from low automation, inadequate segmentation performance, and limited classification accuracy.
arxiv  

Population Pharmacokinetic/Toxicodynamic Model for Polymyxin B in Critically Ill Patients to Identify the Risk of Nephrotoxicity

Clinical Pharmacology &Therapeutics, EarlyView.
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin, Ramya Mahadevan, Gauri G. Rao, Alexandre P. Zavascki, Ana Maria Sandri, Andrea Kwa, Marc H. Scheetz, Christine J. Kubin, Jayesh Shah, Benjamin P.Z. Cherng, Michael T. Yin, Jiping Wang, Lu Wang, David P. Calfee, Maureen Bolon, Anthony W. Purcell, Roger L. Nation, Jason M. Pogue, Jian Li, Keith S. Kaye   +19 more
wiley   +1 more source

The Prevalence of Metallo-β-lactamase (MBL) in Gram Negative Bacilli and their Antimicrobial Susceptibility Pattern at Tertiary Care hospital, Vadodara

GAIMS Journal of Medical Sciences
Background: Antimicrobial resistance is the major threat due to broad spectrum antimicrobials are being used in community practice. The Metallo-β-lactamases (MBLs) in gram negative bacteria have emerged as a major cause of health care associated ...
Nisarg Trivedi, Mitesh Kamothi, Bhavesh Gohil, Hitesh Assudani   +3 more
doaj   +1 more source

Fine Structure of Strictly Anaerobic, Non‐Spore‐Forming, Gram‐Negative Bacilli [PDF]

, 1967
Tsutomu Ushijima
openalex   +1 more source

A Simple Strategy for Co‐Immobilization of NADH‐Dependent Enzymes and NADH for Efficient Biocatalysis in Continuous Flow Reactors

ChemSusChem, EarlyView.
Polyethylenimine‐modified Cry3Aa‐formate dehydrogenase (FDH)/Cry3Aa‐leucine dehydrogenase (LDH) fusion particles entrapped in agarose beads enables efficient NADH recycling, thereby facilitating the continuous synthesis of chiral intermediates in a flow reactor.
Reza Yekta, Xu Xiong, Marianne M. Lee, Michael K. Chan   +3 more
wiley   +1 more source

A bacteriological study of diabetic foot infection in an urban tertiary care hospital of Dhaka city

IMC Journal of Medical Science, 2009
Identification of organisms and effective antibiotic therapy is an important component of treatment of diabetic foot infections. This study was undertaken to determine the organisms associated with diabetic foot infection (DFI) and their antibiotic ...
Samir Paul, Lovely Barai, Ashraf Jahan, J. Ashraful Haq   +3 more
doaj