Results 211 to 220 of about 430,389 (345)

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Antibiotic Therapy Duration for Multidrug-Resistant Gram-Negative Bacterial Infections: An Evidence-Based Review. [PDF]

Int J Mol Sci
Marino A, Augello E, Bellanca CM, Cosentino F, Stracquadanio S, La Via L, Maniaci A, Spampinato S, Fadda P, Cantarella G, Bernardini R, Cacopardo B, Nunnari G.   +12 more
europepmc   +1 more source

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

Advanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang, Yao Shen, Juan Liu, Qing Zeng, Yunze Ma, Shuping Chen, Taiyu Nan, Xiaoying Qiu, Jiayi Yu, Tao Fan, Guozhi Huang, Jihua Zou, Chengduan Yang   +12 more
wiley   +1 more source

A nontoxic, idiotope vaccine against gram-negative bacterial infections. [PDF]

, 1992
Shuai Su, Michael M. Ward, Michael A. Apicella, R. Ward   +3 more
openalex   +1 more source

Efficacy and safety of ceftazidime-avibactam versus standard antibiotic therapy for resistant Gram-negative bacterial infections: a systematic review and meta-analysis. [PDF]

J Thorac Dis
Li J, Dong Z, Tang L, Liu L, Yu S.
europepmc   +1 more source

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic intestinal inflammation and impaired barrier function, for which effective long‐term therapies remain elusive. To address this challenge, we developed a novel nano‐vaccine that combines Prussian blue nanozymes (PBNZs) adjuvants with a ferritin carrier loaded with ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

A Comparative Study of Ceftazidime-Avibactam and Meropenem-Based Regimens in the Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections in Intensive Care Units. [PDF]

Antibiotics (Basel)
Aydın M, Aydın NN, Aslan MH, Kahramanoğlu M.   +3 more
europepmc   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

Harnessing endogenous anti-glycan antibodies using a novel, bifunctional immunotherapy to treat gram-negative bacterial infections. [PDF]

J Immunol
Hairsine B, Leire E, Rostam HM, Kristian SA, Rhodes E, Johnson A, Bushdyhan M, Chapman D, Pickford C, Westby M, Bright H.   +10 more
europepmc   +1 more source

Status of Antibiotic Susceptibility of Polymyxin B And Colistin in the Treatment of Carbapenem Resistant Gram Negative Bacterial Infections: An Observational Study

Ashish Kumar Bhattarai, Khilasa Pokharel, Marina Vaidya Shrestha   +2 more
openalex   +1 more source