Results 301 to 310 of about 430,389 (345)

Pathogenesis of Gram-Negative Bacterial Infections

1988
Gram-negative micro-organisms such as Enterobacteriaceae and Pseudomona-ceae are a normal part of the flora of the digestive tract. This close and peaceful coexistence may reflect a relatively low virulence of the bacteria. However, invasion of the blood stream can occur under certain circumstances, and may cause a life-threatening disease with ...
J. F. P. Schellekens, J. Verhoef
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Treatment of Gram-negative bacterial infections by potentiation of antibiotics

Current Opinion in Microbiology, 2016
Infections caused by antibiotic-resistant pathogens, particularly Gram-negative bacteria, represent significant treatment challenges for physicians resulting in high rates of morbidity and mortality. The outer membrane of Gram-negative bacteria acts as a permeability barrier to many compounds that would otherwise be effective antibacterial agents ...
Thomas P, Zabawa, Michael J, Pucci, Thomas R, Parr, Troy, Lister   +3 more
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Developments on antibiotics for multidrug resistant bacterial Gram-negative infections

Expert Review of Anti-infective Therapy, 2019
Introduction: The constantly increasing spread of severe infections due to multidrug-resistant (MDR) Gram-negative bacteria (GNB) is a critical threat to the global medical community. After a long period of antibiotic pipeline pause, new antibiotic compounds are commercially available or are at late stages of clinical evaluation, promising to augment ...
Georgios L, Voulgaris, Maria L, Voulgari, Matthew E, Falagas   +2 more
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Gram-negative bacterial infections of the mammary gland in cows

American Journal of Veterinary Research, 1991
SUMMARY Naturally acquired gram-negative bacterial intramammary infections (n= 160) were studied in 99 cows over a 2-year period. Escherichia coli, Klebsiella spp, Serratia spp, Enterobacter spp, and unidentified gram-negative bacteria were isolated from 28.8, 39.4, 9.4, 5.0, and 11.2%, respectively, of infected mammary glands.
D A, Todhunter, K L, Smith, J S, Hogan, P S, Schoenberger   +3 more
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Gram-negative bacterial infection of aortic aneurysms.

The Journal of cardiovascular surgery, 1987
Widespread use of antibiotics and change in pathogenesis altered the bacteriology of infected aortic aneurysms. In the past, bacterial endocarditis was the major source of emboli infecting the aorta. Now, gram-negative sepsis in elderly patients is often the initiating event of infection in atherosclerotic aneurysms.
M F, McNamara, A B, Roberts, K R, Bakshi
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Gram-negative bacterial skin infections.

Seminars in dermatology, 1994
The gram-negative bacilli are a very diverse group of organisms with varied antimicrobial resistance patterns and degrees of pathogenicity. In consequence, it is difficult to make confident statements on appropriate therapies. Here the most common types of infections, or infecting organisms, are described together with reported successful therapies.
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New treatment modalities for serious Gram-negative bacterial infections

International Journal of Antimicrobial Agents, 1993
Despite the use of potent antimicrobial agents and advanced supportive care, the mortality rate of patients with Gram-negative bacteremia remains high (between 20 and 35%). In patients with Gram-negative bacteremia who develop septic shock, the mortality rate may be as high as 50-80% [1-4].
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Immunoprophylaxis and Immunotherapy of Gram-negative Bacterial Infections

1994
Over the last decades the incidence of gram-negative bacterial infections has risen markedly in most medical centres1,2. At the Boston City Hospital, the incidence of gram-negative bacteraemia increased from 0.9/1000 admissions in 1935 to 11.2/1000 admissions in 19723.
J. D. Baumgartner, M. P. Glauser
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Gram-Negative Bacterial Infections

2021
Virginia Sinnott-Stutzman, Jane E. Sykes
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The evolution of knowledge for treating Gram-negative bacterial infections

Current Opinion in Infectious Diseases
Purpose of review Infections caused by nonprimarily pathogenic Gram-negative bacilli (GNB) have been increasingly reported from the second half of the 20th century to the present. This phenomenon has expanded during the antibiotic era and in the presence of immunodeficiency. Before the discovery of sulphonamides and
Almudena, Burillo, Emilio, Bouza
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