Results 31 to 40 of about 627,357 (262)

Gram-Positive Rods on a Cerebrospinal Fluid Gram Stain [PDF]

Open Forum Infectious Diseases, 2017
Abstract Cerebrospinal fluid (CSF) access device placement in the pediatric population presents challenges due to the development of infections following placement, access or revision, and/or shunt malfunctions. Here we report an unusual pediatric case of L.
Thompson, Amelia B, Wrubel, David, Berkowitz, Frank E   +2 more
openaire   +2 more sources

Machine learning model for the prediction of gram-positive and gram-negative bacterial bloodstream infection based on routine laboratory parameters

BMC Infectious Diseases, 2023
Background Bacterial bloodstream infection is responsible for the majority of cases of sepsis and septic shock. Early recognition of the causative pathogen is pivotal for administration of adequate empiric antibiotic therapy and for the survival of the ...
Fan Zhang, Hao Wang, Liyu Liu, Teng Su, Bing Ji   +4 more
doaj   +1 more source

Antimicrobial Resistant Bacteria Isolated from Intensive Care Units

Indonesian Journal of Innovation and Applied Sciences, 2023
Aimed to determine the kind of microorganisms probably to be gifted inside the in-depth care unit and the suitable antibiotics for them. ‏Methods use the duration between October and December 2021‏.
Eman Muftah Elzouki, Najah Ahmeda Ibrahim, Salwa Muftah Eljamay, Aisha M. Bojazyah   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The SaeRS two-component system regulates virulence gene expression in group B Streptococcus during invasive infection

mBio
Group B Streptococcus (GBS) is a pathobiont responsible for invasive infections in neonates and the elderly. The transition from a commensal to an invasive pathogen relies on the timely regulation of virulence factors. In this study, we characterized the
Francesco Coppolino, Giuseppe Valerio De Gaetano, Cosme Claverie, Odile Sismeiro, Hugo Varet, Rachel Legendre, Angelica Pellegrini, Alessia Berbiglia, Luca Tavella, Germana Lentini, Agata Famà, Giulia Barbieri, Giampiero Pietrocola, Giuseppe Teti, Arnaud Firon, Concetta Beninati   +15 more
doaj   +1 more source

Antimicrobial potential of Streptomyces sp. to the Gram positive and Gram negative pathogens

Journal of Infection and Public Health, 2019
Background: The occurrence of drug resistant infectious disease causing microbial pathogens was highly spreaded because of the wide level application of the commercially available antimicrobial agents.
Mysoon Al-Ansari, Noorah Alkubaisi, P. Vijayaragavan, K. Murugan   +3 more
doaj   +1 more source

Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms

mBio, 2022
Ceragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of action is similar to
Gabriel Mitchell, Melanie R. Silvis, Kelsey C. Talkington, Jonathan M. Budzik, Claire E. Dodd, Justin M. Paluba, Erika A. Oki, Kristine L. Trotta, Daniel J. Licht, David Jimenez-Morales, Seemay Chou, Paul B. Savage, Carol A. Gross, Michael A. Marletta, Jeffery S. Cox   +14 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Antimicrobial Resistance Profiles in Enterococcus spp. Isolates From Fecal Samples of Wild and Captive Black Capuchin Monkeys (Sapajus nigritus) in South Brazil

Frontiers in Microbiology, 2018
The environment, human, and animals play an important role in the spread of antibiotic-resistant bacteria. Enterococci are members of the gastrointestinal tracts of humans and animals and represent important reservoirs of antibiotic resistance genes ...
Tiela Trapp Grassotti, Dejoara de Angelis Zvoboda, Letícia da Fontoura Xavier Costa, Alberto Jorge Gomes de Araújo, Rebeca Inhoque Pereira, Renata Oliveira Soares, Paulo Guilherme Carniel Wagner, Jeverson Frazzon, Ana Paula Guedes Frazzon   +8 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source