Results 201 to 210 of about 758,404 (298)

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +2 more sources

Clinical implementation of endolysins targeting gram-positive bacteria points toward a combination strategy with standard-of-care antibiotics: a selective review. [PDF]

Eur J Med Res
Vander Elst N.
europepmc   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose

Angewandte Chemie, EarlyView.
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon, Xianjin Qin, Marjon Zamani, Ariel L. Furst, Cassandra E. Callmann   +4 more
wiley   +2 more sources

A strategy to re-sensitise drug-resistant Gram-positive bacteria to oxazolidinone-class antibiotics. [PDF]

EBioMedicine
Zhang Q, Yang Y, Yang Y, Shang J, Su S, Gao P, Li XX, Liu Z, Kao RY, Ko BC, Thompson B, Zhao Q.   +11 more
europepmc   +1 more source

Clinical impact and disparities in mortality and antimicrobial resistance between Gram-negative and Gram-positive bacteria in cirrhotic abdominal infections: a meta-analysis. [PDF]

Front Med (Lausanne)
Xie XQ, Shao JW.
europepmc   +1 more source

Interactions of <i>Galleria mellonella</i> Proline-Rich Antimicrobial Peptides with Gram-Negative and Gram-Positive Bacteria. [PDF]

Int J Mol Sci
Zdybicka-Barabas A, Stączek S, Mak P, Kapral-Piotrowska J, Skrzypiec K, Wydrych J, Pawlikowska-Pawlęga B, Gruszecki WI, Cytryńska M.   +8 more
europepmc   +1 more source

The avermectin, emamectin benzoate, kills gram-positive bacteria and targets the cell envelope of <i>Bacillus subtilis</i>. [PDF]

Microbiol Spectr
Ahmad R, Lewis D, Verellen LA, Yin R, Scott A, Fruci M.   +5 more
europepmc   +1 more source

Selenocompounds as Potent Efflux Pump Inhibitors on Gram-positive Bacteria. [PDF]

ChemMedChem
Kincses A, Szemerédi N, Benito-Lama M, Dózsai D, Csonka Á, Domínguez-Álvarez E, Spengler G.   +6 more
europepmc   +1 more source

Presence of viable gram-positive bacteria in blood of patients with inflammatory bowel disease is not affected by treatment. [PDF]

Sci Rep
Davidson S, So Y, Oscarsson E, Håkansson Å, Sjöberg K.   +4 more
europepmc   +1 more source