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New agents for Gram-positive bacteria
Current Opinion in Microbiology, 2000Infections caused by multiple-resistant Gram-positive organisms continue to occur at an alarming rate worldwide. Two new and unique antimicrobial agents targeted specifically against such organisms, quinupristin/dalfopristin and linezolid, have been approved for use in the USA in the past year and will play an important role in the treatment of life ...
S M, Bhavnani, C H, Ballow
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Surface Display on Gram Positive Bacteria
Combinatorial Chemistry & High Throughput Screening, 2012Heterologous surface display on Gram-positive bacteria was first described almost a decade ago and has since then developed into an active research area. Gram-positive bacterial surface display has today found a range of applications, in immunology, microbiology and biotechnology. Live bacterial vaccine delivery vehicles are being developed through the
M, Hansson +3 more
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Pilus Assembly in Gram-Positive Bacteria
2015Pili of Gram-positive bacteria are unique structures on the bacterial surface, assembled from covalently linked polypeptide subunits. Pilus assembly proceeds by transpeptidation reactions catalyzed by sortases, followed by covalent anchoring of the filament in the peptidoglycan layer.
Werner, Pansegrau, Fabio, Bagnoli
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Vaginal Immunization with Recombinant Gram‐Positive Bacteria
American Journal of Reproductive Immunology, 1998PROBLEM: Many viral and bacterial pathogens enter the body through the genital mucosa. Therefore, one of the major goals of a vaccine against sexually transmitted diseases (STDs) should be to induce an immune response in the genital mucosa capable of controlling the entry of the pathogen.
Medaglini D., Oggioni M. R., Pozzi G.
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Protein Secretion in Gram-Positive Bacteria
2003Studies on protein secretion in Gram-positive bacteria have become of particular importance since many species are of great commercial value and medical interest. Several Gram-positive bacteria have been applied successfully for cost-effective industrial production of enzymes since, due to the absence of an outer membrane, proteins are secreted ...
Meima, Rob, van Dijl, Jan Maarten
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Gram-positive brewery bacteria
1996Bacteria have been recognized as important spoilage agents of beer since the end of the nineteenth century. Comparison of the descriptions of bacteria prevalent in breweries and beers at that time with those of today reveals that the range of bacteria encountered is remarkably constant, although the names have been changed frequently over the years ...
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Protein secretion in Gram-positive bacteria
Journal of Biotechnology, 1992Gram-positive bacteria often secrete large amounts of proteins into the surrounding medium. This feature makes them attractive as hosts for the industrial production of extracellular enzymes. Compared to Escherichia coli, relatively little is known about the mechanism of protein secretion in these organisms.
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