Results 71 to 80 of about 1,304 (204)

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

PHGDH Orchestrates Cell Cycle Progression to Drive Cardiomyocyte Proliferation and Myocardial Regeneration via TGF‐β/Smad Signalling Pathway

open access: yesCell Proliferation, EarlyView.
PHGDH promoted cardiomyocyte proliferation and myocardial regeneration via cell cycle and TGF‐β/Smad signalling pathways during cardiac repair. Moreover, PHGDH benefits cardiac repair and cardiomyocyte proliferation in mammalian mice following MI. ABSTRACT The mature mammalian heart has limited ability for self‐repair and regeneration.
Han Zhang   +6 more
wiley   +1 more source

Expressive language and social communication abilities in children with spinal muscular atrophy type 1

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To investigate parent‐reported expressive language and social communication abilities in children with spinal muscular atrophy type 1 (SMA1) treated with disease‐modifying therapies. Method This was a cross‐sectional feasibility study performed at the Dubowitz Neuromuscular Centre, London (UK), and the Centro Clinico Nemo Pediatrico, Rome (
Chiara Brusa   +19 more
wiley   +1 more source

Understanding the Burden of Work‐Related Musculoskeletal Disorders in Dental Students: A Multinational Cohort Study

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction To evaluate the prevalence and potential risk factors of work‐related musculoskeletal disorders (WMSDs) among fifth‐year dental students from Romania, Türkiye, Serbia, North Macedonia and Montenegro. Materials and Methods A prospective questionnaire‐based survey was conducted, including demographics, the Nordic Musculoskeletal ...
Özlem Daltaban   +8 more
wiley   +1 more source

Unsolvable Riddles and the Truth of Skepticism: Wittgenstein and Cavell

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract Both Wittgenstein and Cavell see riddles as a model of intellectual difficulty. By drawing attention to it, they remind us that not all of our intellectual challenges take the form of empirically answerable questions—there may be cases of our not merely lacking knowledge, but of being caught in the fantasy that a certain type of knowledge can ...
Gilad Nir
wiley   +1 more source

Our(?) Concept of Food or, They are Eating Their Pets

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract This article examines the idea that deep disagreements are best understood as rooted in conceptual differences rather than differences in judgments and opinions, by means of a reflection on the differences between a vegan and a meat eater. The aim is not to develop a new theory of “deep disagreement” but to gain clarity about one field in ...
Niklas Forsberg
wiley   +1 more source

A teacher educator's return to P‐12 world language teaching: Transforming practices, perspectives, and identities

open access: yesForeign Language Annals, EarlyView.
Abstract After working at a university as a language teacher educator for 20 years, I returned to the P‐12 setting to coteach an inclusive high school Spanish class. The purpose of this return was to relearn to teach and to better understand current challenges in language education, student engagement, and inclusive instruction.
Beth Wassell
wiley   +1 more source

Systemic N‐Acylethanolamines and Other Lipid Mediators Are Associated With NSAID‐Exacerbated Respiratory Disease

open access: yes
Clinical &Experimental Allergy, EarlyView.
Viljami E. Salmi   +5 more
wiley   +1 more source

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