Results 91 to 100 of about 9,707,299 (330)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

The acquisition of Greek case, number, and gender: a usage based approach [PDF]

open access: yes, 2007
Children […] growing up with highly inflected languages such as Modern Greek will frequently hear different grammatical forms of a given lexeme used in different grammatical and semantic-pragmatic contexts. In spite of the fact that the Greek noun is not
Christofidou, Anastasia   +1 more
core  

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

open access: yesAdvanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai   +8 more
wiley   +1 more source

The acquisition of grammatical gender in L2 German by learners with Afrikaans, English or Italian as their L1

open access: yesStellenbosch Papers in Linguistics, 2012
In recent years there has been an increase in research on the acquisition of morphological aspects of a second language (L2). Specifically, a number of studies have been conducted on the acquisition of grammatical gender in the L2.
Ellis, Carla   +2 more
doaj   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Descriptivity grading of finnish body-part terms [PDF]

open access: yes, 1975
Three quantificational approaches to the measurement of lexical descriptivity are proposed, based on: the semantic sum of the parts of a lexeme is equal to the whole, paraphrase-term and term-paraphrase congruence, explicitness of semantic elements of a ...
Ultan, Russell
core  

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

open access: yesAdvanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao   +7 more
wiley   +1 more source

Is Inuktitut a morphological argument language? [PDF]

open access: yes, 2009
In the following I will discuss grammatical structures of Inuktitut, an Eskimo language spoken in the Canadian Eastern Arctic. Inuktitut is a polysynthetic language exhibiting an exceedingly elaborate verbal inflectional system including polypersonal ...
Nowak, Elke
core  

STUDENTS’ GRAMMATICAL COLLOCATION ERRORS AND ITS’ IMPLICATION IN TEACHING WRITING

open access: yesIJET (Indonesian Journal of English Teaching), 2016
The Regulation of Minister of Education and Culture of the Republic of Indonesia number 49 2014 on National Standard of Higher Education stated that National Standard Research is the minimum criterion of research on higher education system in force in ...
Sayyidatul Fadlilah
doaj   +1 more source

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