Results 41 to 50 of about 3,857 (232)

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Grammatical replacements in translation of German advertising texts of utomotive subject including participial constructions with attributive meaning

Russian journal of linguistics: Vestnik RUDN, 2013
Informative capacity of participial construction of source and target languages contributes to a more complex and multi aspect image of an expensive car.
A N Mamedov
doaj  

On cultural dialects in Slavic ethnolinguistics [PDF]

Južnoslovenski Filolog, 2016
In the article the author considers the basic ideas of the Moscow ethnolinguistic school on the basis of several examples from the South Slavic cultural dialects.
Plotnikova Anna A.
doaj   +1 more source

Discourse Reconstruction in the English Translation of Sunzi’s The Art of War: A Grammatical Cohesion Perspective

Theory and Practice in Language Studies
This study investigates discourse reconstruction in translating Sunzi’s The Art of War from classical Chinese into English, focusing on how translators adapt grammatical cohesion devices to enhance readability and contribute to discourse reconstruction in the target text. The study employs a mixed-method approach, combining corpus analysis (via AntConc
Lei Chen, Muhammad Alif Redzuan Abdullah, Syed Nurulakla bin Syed Abdullah, Yanan Yang   +3 more
openaire   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Reconstructing The Function of Supreme Court Circular Letters As Internal Policy Regulations To Strengthen Judicial Supervision And The Uniformity of Judicial Practice

Yurisdiksi: Jurnal Wacana Hukum dan Sains
This study examines the reconstruction of the function of Supreme Court Circular Letters (Surat Edaran Mahkamah Agung/SEMA) as internal policy regulations in strengthening judicial supervision and promoting the uniformity of judicial practice in ...
Muhotim, Aan Eko Widiarto, Dhia Al Uyun
doaj   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Regulatory Framework for Social Mapping  in Structuring Access to Agrarian Reform

Yurisdiksi: Jurnal Wacana Hukum dan Sains
the structuring of agrarian reform access and to formulate an ideal regulatory framework to ensure legal certainty. This research employs a normative juridical method using statutory, conceptual, and comparative approaches.
Nur Laili Safitri, Herlindah, Arini Jauharoh   +2 more
doaj   +1 more source

Holistic Linguistics: Anthropocentric Foundations and the Functional-Cognitive Paradigm

Prague Journal of English Studies, 2015
This paper dwells on some aspects of language, grammar in particular, through the prism of the functional-cognitive approach. It covers such issues as language and mind, the embodiment of language, the peculiarities of language acquisition, and the ...
Tyurkan (Belichenko) Elena
doaj   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source