Results 201 to 210 of about 7,457 (299)

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Sound-symbol correspondence in autism: The <i>Bouba</i>-<i>Kiki</i> effect. [PDF]

Res Autism
Prescott KE, Larson C, Stabile MJ, Eigsti IM.   +3 more
europepmc   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Language in vivo vs. in silico: Size matters but Larger Language Models still do not comprehend language on a par with humans due to impenetrable semantic reference. [PDF]

PLoS One
Dentella V, Günther F, Leivada E.
europepmc   +1 more source

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source

ABCD: A Simulation Method for Accelerating Conversational Agents With Applications in Aphasia Therapy. [PDF]

J Speech Lang Hear Res
Imaezue GC, Marampelly H.
europepmc   +1 more source

Training on the quadriceps of individuals with rheumatoid arthritis: A systematic review and meta‐analysis

Rheumatology &Autoimmunity, EarlyView.
Physical training significantly improves quadriceps strength in patients with rheumatoid arthritis. No serious adverse events were reported. Abstract Background Rheumatoid arthritis is a chronic, systemic disease in which patients can benefit from physical exercise.
Mariana Laís Boaretto, Diego Francis Saraiva Rodriguez, Dartel Ferrari de Lima, Cristiane Buzanello Donin, Alberito Rodrigo de Carvalho, Márcia Rosângela Buzanello, Gladson Ricardo Flor Bertolini   +6 more
wiley   +1 more source

Without safeguards, AI-Biology integration risks accelerating future pandemics. [PDF]

Front Microbiol
Wang D, Huot M, Zhang Z, Jiang K, Shakhnovich EI, Esvelt KM.   +5 more
europepmc   +1 more source

Robotics for Crop Pollination: Recent Advances and Future Direction

Journal of Field Robotics, EarlyView.
ABSTRACT There is great interest in alternative pollination strategies for crop production in the face of climate change and perennial threats to the traditional pollination mechanisms. This review explores the potential of robotic pollination as a promising solution to these challenges affecting crop fertilization, agricultural sustainability, and ...
Ranjan Sapkota, Matthew D. Whiting, Dawood Ahmed, Manoj Karkee   +3 more
wiley   +1 more source

Who Can Afford to Fail? Investigating Science Students' Perceptions of Failure Through the Lens of Their Identities

Science Education, EarlyView.
ABSTRACT Scientists agree that learning to cope with failures is an important skill for science students to develop, and students who participate in science research often have positive outcomes after coping with science failures. However, the experience of failure in undergraduate science education more broadly seems to have an overall negative impact
Sandhya Krishnan, Isobel D. Cobb, Joseph A. Harsh, Manuela Mejia, Lisa Corwin   +4 more
wiley   +1 more source