Results 31 to 40 of about 10,910 (292)

Qualitative study of grammaticalization, constructional change and constructionalization phenomena in the English progressive construction

open access: yesCuadernos de Investigación Filológica, 2020
In this paper we examine qualitatively certain grammatical change phenomena undergone by English progressive constructions during their diachronic development.
Carlos van Arkel-Simón
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Étude d’un schéma d’évolution conceptuelle des ‘grams’ spatiaux en relation avec ahead et in front of en anglais

open access: yesCorela, 2004
Many grammatical items with a spatial and/or a temporal meaning (‘grams’) are the result of a process of grammaticalization which creates complex metaphorical and metonymical chains.
Hélène Margerie
doaj   +1 more source

Grammaticalization and grammar [PDF]

open access: yes, 1992
This paper is concerned with developing Joan Bybee's proposals regarding the nature of grammatical meaning and synthesizing them with Paul Hopper's concept of grammar as emergent. The basic question is this: How much of grammar may be modeled in terms of
Himmelmann, Nikolaus P.
core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

The Grammaticalization of Modal Verbs in Brazilian Portuguese: A Synchronic Approach

open access: yesJournal of Portuguese Linguistics, 2016
This paper analyzes the grammaticalization of modal verbs in Brazilian Portuguese from a synchronic perspective. It takes as its point of departure the hypothesis that grammaticalization is a process in which linguistic elements widen their scope.
Kees Hengeveld   +1 more
doaj   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Língua falada e gramaticalização

open access: yesFilologia e Linguística Portuguesa, 1997
Under the assumption of the modularity of language, I propose discoursivization, semanticalization and grammaticalization as constitutive processes of spoken language.
Ataliba T. de Castilho
doaj   +1 more source

Dynamic Syntax and dialogue modelling: preliminaries for a dialogue-driven account of syntactic change [PDF]

open access: yes, 2006
This paper sets out an account of grammaticalization in the framework of Dynamic Syntax (DS) in which the emergence of object clitics in Medieval Spanish and the change in their syntactic positioning in Renaissance Spanish are shown to be driven by ...
Ruth M. Kempson   +3 more
core   +1 more source

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