Effects of HMG CoA reductase (HMGCR) deficiency on skeletal muscle development
Three skeletal muscle diseases are linked to HMGCR, a key enzyme in cholesterol synthesis. These diseases include a muscular dystrophy associated with pathogenic variants in the HMGCR gene, statin‐associated myopathy, and autoimmune anti‐HMGCR myopathy.
Mekala Gunasekaran+20 more
wiley +1 more source
Azores marine algal flora: how endangered is it? [PDF]
Unesco chair for "Conservation of plant biodiversity in Macaronesia and the West of Africa", Gran Canaria, 27-28 November ...
Neto, Ana I.
core
Adaptive Reproductive Strategies of Limpets in a Harvest‐Influenced Environment
ABSTRACT Limpet harvesting is a size‐selective activity that primarily removes the largest individuals, leading to reduced reproductive output. This study investigates the fecundity strategies of two limpet species, Patella aspera and Patella crenata, inhabiting the rocky shores of Gran Canaria.
Joana Vasconcelos+5 more
wiley +1 more source
Aims The aim of this study was to determine the clinical profile, associated events and safety of vericiguat in a real‐world cohort of patients with heart failure with reduced ejection fraction (HFrEF).
Mario Galván Ruiz+8 more
doaj +1 more source
Gender diversity and autism spectrum disorder in child and youth population
Introduction Interest in the co-occurrence of gender dysphoria and autism spectrum disorder has gained prominence in recent years. Gender dysphoria refers to the distress experienced when there is an incongruence between gender identity and sex assigned
P. R. Rodríguez+4 more
doaj +1 more source
Proposal and Comparative Study of Evolutionary Algorithms for Optimum Design of a Gear System [PDF]
This paper proposes a novel metaheuristic framework using a Differential Evolution (DE) algorithm with the Non-dominated Sorting Genetic Algorithm-II (NSGA-II).
Frutos, Mariano+3 more
core +1 more source
Species traits modulate ecological release in island red devil spiders (Araneae: Dysderidae)
We studied the species ability to undergo an ecological release process in the red devil spiders (Araneae: Dysderidae) when colonising species‐depauperate environments, focusing on different aspects of their niche. We have found that the ability to expand their niche is highly dependent on the species trophic strategy, with specialist species being ...
Adrià Bellvert+5 more
wiley +1 more source
Análisis espacial de los ingresos obtenidos por alojamientos de turismo rural en Gran Canaria: hacia una nueva propuesta al modelo estandarizado por el SIG [PDF]
Este trabajo intenta demostrar la existencia de alguna relación directa entre los ingresos obtenidos por los alojamientos de turismo rural en Gran Canaria y su localización.
Um Flores, Erika
core
Consensus on core domains for hand eczema trials: Signs, symptoms, control and quality of life
A core domain set for hand eczema was developed in an international consensus study with an online Delphi survey and a consensus meeting. Signs and symptoms of hand eczema, related quality of life and control over time should be measured in all future hand eczema therapeutic trials.
Henriette Rönsch+38 more
wiley +1 more source
La arquitectura racionalista de Miguel Martín y la ciudad de Las Palmas de Gran Canaria = The Rationalist Architecture of Miguel Martín and the City of Las Palmas [PDF]
La arquitectura racionalista de Miguel Martín y la ciudad de Las Palmas de Gran Canaria = The Rationalist Architecture of Miguel Martín and the City of Las ...
Cortés, Juan Antonio
core +1 more source