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Results 171 to 180 of about 265,113 (290)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source

Hodgkin and non‐Hodgkin lymphomas in the post‐antiretroviral therapy era according to HIV virological suppression

HIV Medicine, EarlyView.
Abstract Objectives Lymphomas remain among the most frequent HIV‐associated malignancies, with risk persisting despite effective virological control. This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non‐Hodgkin [NHL]) in people living with HIV (PLWH), according to virological ...
Teresa Aldámiz‐Echevarria +555 more
wiley +1 more source

High-fidelity simulation in airway management training: results from the AIR-MASTER-SIM randomised study. [PDF]

Front Med (Lausanne)
Puerma-Jiménez J +7 more
europepmc +1 more source

Priority areas for arthropod conservation in the Iberian Peninsula and Balearic Islands: Insights from a multi‐taxon distributional database

Insect Conservation and Diversity, EarlyView.
Using over 416,000 occurrence records from 13 arthropod groups (6233 arthropod species), we mapped large‐scale richness patterns and identified biodiversity hotspots across the Iberian Peninsula and Balearic Islands. Hotspot congruence among arthropod groups was low, underscoring the importance of integrative, multi‐taxon approaches for conservation ...
David Sánchez‐Fernández +30 more
wiley +1 more source

Reply to Arroyo et al.: Universality and diversity in thermal performance curves. [PDF]

Proc Natl Acad Sci U S A
Arnoldi JF +3 more
europepmc +1 more source

Diet breadth shapes gut microbiota in the invasive hornet Vespa velutina

Insect Conservation and Diversity, EarlyView.
Dietary and microbial profiles of V. velutina larvae are dominated by Apidae and Firmicutes, respectively. DNA metabarcoding of larval meconium and gut samples reveals a significant positive correlation between prey richness and bacterial diversity in the invasive hornet V. velutina. Multiple significant correlations exist between dietary and microbial
Cayetano Herrera +3 more
wiley +1 more source

The impact of vasectomy on the seminal microbiome: possible implications and source of microbes. [PDF]

Hum Reprod Open
Molina NM +13 more
europepmc +1 more source

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco +5 more
wiley +1 more source

Diagnostic Performance and Misclassification Patterns of Preoperative MRI in Rectal Cancer: A Real-World Study. [PDF]

Diagnostics (Basel)
Luengo Gómez D +7 more
europepmc +1 more source

Giving a Voice to Survivors: A Critical Discourse Analysis of Women's Narratives of Sexual Violence

International Journal of Applied Linguistics, EarlyView.
ABSTRACT Sexual violence constitutes a pervasive global issue, disproportionately affecting women and girls and resulting in serious health consequences, making it essential to give a voice to survivors. This study employed the transitivity model to analyse the discourse of women survivors, focusing on how they recount and interpret their experiences ...
Marta Badenes Sastre +2 more
wiley +1 more source

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