Results 91 to 100 of about 4,217,946 (332)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Foundation Giving in North Carolina: An Analysis of Trends for Fiscal Year 2006 [PDF]
, 2008 Provides an overview of giving by the state's foundations, organized by type of foundation, grants awarded, total giving, assets, county, and subject area.
Anita Gunn Shirley
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Економіка, управління та адмініструванняThis article conducts an in-depth analysis of the critical importance of international financial assistance in supporting and rebuilding Ukraine's economy under the challenging conditions of the prolonged conflict with russia.
V.А. Panchenko
doaj +1 more source
Options and limitations in measuring the impact of research grants—evidence from Denmark and Norway
, 2015 Competitive grant schemes are set up with the intention of improving research performance. It may, however, be difficult to find evidence of the intervention impact of research grants for ex post evaluations of grant schemes.
Liv Langfeldt, C. Bloch, G. Sivertsen
semanticscholar +1 more source
Stimulating Local Public Employment: Do General Grants Work?
Social Science Research Network, 2014 We apply the regression kink design to the Swedish grant system and estimate causal effects of intergovernmental grants on local public employment. Our robust conclusion is that grants do not stimulate local public employment.
Heléne Lundqvist +2 more
semanticscholar +1 more source
Oak Foundation Belize: Annual Summary Report 2012 [PDF]
, 2013 In 2006 Oak Foundation developed a ten-year strategic plan that guides its grant-making in Belize and the wider Mesoamerica region. The purpose of this report is to provide a detailed description of regional grantmaking in 2012 and inform on the progress
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 2006 Philanthropy's primary funding strategy -- restricted grants -- too often hamstrings grantees' ability to plan, invest, and respond to changes with vision, flexibility, and innovation. Since its inception, the F.B.
John Weiler
core