Results 131 to 140 of about 1,616,654 (263)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A novel surname-based methodology to improve the disaggregation of Asian American ethnic subgroups in patients with ovarian cancer. [PDF]

Gynecol Oncol Rep
Lee SS, Gold HT, Ðoàn LN, Kwon SC, Pothuri B.   +4 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Grants & Grant Outcomes [PDF]

Health Affairs, 2002
openaire   +2 more sources

Air pollution and the risk of second primary lung cancer among lung cancer survivors: the prospective UK Biobank cohort study. [PDF]

Br J Cancer
Choi E, Luo S, Ding VY, Graber-Nadich A, Wu JT, Popat R, Cheng I, Neal JW, Wakelee HA, Han SS.   +9 more
europepmc   +1 more source

Grants & Grant Outcomes [PDF]

Health Affairs, 2004
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The European Union's Civil Society Strategy: a welcome milestone that now requires sustained operational support. [PDF]

Health Aff Sch
Rajan D.
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Reply: Rethinking sustained recompensation in MASLD cirrhosis: The value of pharmacological maintenance. [PDF]

Hepatol Commun
Jiménez-Masip A, Pulido JMP.
europepmc   +1 more source