Results 171 to 180 of about 4,217,946 (332)

Ճապոնիայի տնտեսական քաղաքականությունը Հայաստանում (1992-2021 թթ.)

Banber Arevelagitut'yan Instituti
The purpose of this article is to show the economic policy of Japan towards Armenia after the establishment of Armenian-Japanese diplomatic relations.
Yeva Harutyunyan
doaj  

Current Assessment of Existing Biospecimen Use in Population-Based Cancer Research. [PDF]

Biopreserv Biobank
Hanisch R, Gallicchio L, Daee D, Mahabir S, Nelson S, Carrick DM.   +5 more
europepmc   +1 more source

The Flypaper Effect: Evidence from the Italian National Health System [PDF]

Public expenditure reduction in Italy is achieved through a revision of social security and health care programmes. In particular, public health expenditure control has been implemented through a reform that imposes more stringent budget rules at local ...
Levaggi, Rosella, Zanola, Roberto
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Dynamics of Municipal Fiscal Adjustment [PDF]

The dynamic fiscal policy adjustment of local jurisdictions is investigated empirically using a panel of more than 1000 U.S. municipalities over a quarter of a century.
David E. Wildasin, Thiess Buettner
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Examining the Potential Role of Opioid Settlement Funds in the Face of Impending Federal Budget Reductions for Substance Use Disorders. [PDF]

Health Serv Res
Lindenfeld Z, Mauri AI, Bandara S, Cantor JH, McBain RK, Winiker A.   +5 more
europepmc   +1 more source

Conditional grants to independent regional governments: The trade-off between incentives and wasteful grant-seeking [PDF]

The paper addresses the welfare implications of conditional grants in the presence of inefficiencies in regional production. While conditional grants may set incentives for regions to reduce inefficiencies, resources are wasted in the process of grant ...
Frédéric Blaeschke, Ivo Bischoff
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Use of artificial intelligence for health science in low- and middle-income countries: NIH portfolio landscape, gaps and opportunities. [PDF]

BMJ Open
Forsyth AD, Povlich LK, Kilmarx PH.
europepmc   +1 more source