Results 211 to 220 of about 1,803,229 (305)

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Kuan-modified speckle reducing anisotropic diffusion: A hybrid Bayesian/non-Bayesian method for despeckling SAR images^. [PDF]

MethodsX
Tripathi A, Hudnurkar M.
europepmc   +1 more source

Beyond Primary Nucleation: Molecular Basis of Peptide Crystal Secondary Nucleation at Soft Interface

Advanced Functional Materials, EarlyView.
High spatiotemporal‐resolution atomic force microscopy directly resolved peptide secondary nucleation (SN) and growth characteristics and mechanisms on HOPG. The landscape of peptide nucleation sites, growth dynamics, molecular‐scale structures, phase transitions, and cross‐seeding processes were realized.
Linhao Sun, Abilesh Kumar, Ayhan Yurtsever   +2 more
wiley   +1 more source

Quantum granular-ball generation methods and their application in KNN classification. [PDF]

Sci Rep
Yuan S, Tian X, Lin W, Xia S, Deng JD.
europepmc   +1 more source

Self‐Adaptive Gradient Interphase Enables Durable Solid‐State Lithium Metal Batteries

Advanced Functional Materials, EarlyView.
This work presents a machine learning‐guided interfacial design that forms a self‐adaptive graded interphase on lithium metal anode. A B105M40 composite interlayer evolves into lithiophilic, porous, and fast‐ion‐conducting phases, enabling intimate contact, dendrite suppression, and uniform lithium deposition.
Hongmin Liu, Rui Li, Yitao Lou, Xinran Gao, Min Xu, Shijian Wang, Nana Wang, Huakun Liu, Guoxiu Wang, Zhongchao Bai   +9 more
wiley   +1 more source

Robust Random Walk Based on Natural Neighbors for Outlier Detection. [PDF]

Entropy (Basel)
Chen K, Zhu W, Li T, Wang H.
europepmc   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Advanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik, Yonghui Wang, Kefan Song, Jessica M. Snyder, LeAnn Le, Lauren G. Brown, Shanny Hsuan Kuo, Ashleigh B. Theberge, Suzie H. Pun, Alshakim Nelson   +9 more
wiley   +1 more source

Opportunities and Risks of Technology Convergence in Precision Health. [PDF]

Blockchain Healthc Today
Vasiliu-Feltes I, Bustamante CD, Bischof E, Dennis SJ.   +3 more
europepmc   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Beyond beneficial or ineffective: three-way decision modeling of image-level affective responses to restorative environment design. [PDF]

Front Psychol
Li Q, Zhang C, Li Q, Feng Z.
europepmc   +1 more source