Results 291 to 300 of about 173,747 (363)

Granulation techniques and technologies: recent progresses

open access: yesBioImpacts, 2015
Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules.
S. Shanmugam
exaly   +2 more sources

Granulation time in fluidized bed granulators [PDF]

open access: possiblePowder Technology, 2010
Size enlargement of particles in fluidized bed granulation involves mixing of particles with a binder liquid to form larger wet granules and drying them to form dry granules. Identification of the time for completion of granulation process is critical as further fluidization of dry granules is providing extra energy for their attrition.
Papiya Roy   +2 more
openaire   +1 more source

Alternative Granulation Technique: Melt Granulation

Drug Development and Industrial Pharmacy, 1996
AbstractA melt granulation process has been investigated (1, 2) which efficiently agglomerates pharmaceutical powders for use in both immediate- and sustained-release solid dosage forms. The process utilizes materials that are effective as granulating fluids when they are in the molten state.
Alan Royce   +3 more
openaire   +2 more sources

Effect of the Granulation Process on Nitrofurantoin Granule Characteristics

Drug Development and Industrial Pharmacy, 1998
We studied four granulation methods on the same quantitative and qualitative formula: wet massing by forced agglomeration (Lödige) and free agglomeration (Glatt); and dry massing by slugging and roller compaction technique. Three different particle sizes of nitrofurantoin (bioinequivalent drug) were used. The nitrofurantoin particle size has a very low
Ph. Arnaud   +2 more
openaire   +3 more sources

Effects of High-Shear Granulation on Granulate Homogeneity

Pharmaceutical Development and Technology, 1999
This study considers the effects of particle size of the powder constituents, and of impeller speed on the homogeneity of drug distribution on granulations produced in high-speed mixers. When a micronized low-dose steroid hormone was granulated together with unmicronized lactose in a Vactron 75 high-shear granulator at 250 rpm, strong inhomogeneities ...
Harriette G. M. Poels-Janssen   +2 more
openaire   +3 more sources

Intelligent granules: Are eosinophil crystalloid granules inimitable?

Journal of Allergy and Clinical Immunology, 2010
The controversy surrounding the effector function of eosinophils in health and disease continues at both the clinical and basic discovery levels. Two recent studies reported that an anti-human IL-5 mAb (mepolizumab) specifically targeting eosinophils significantly reduced asthma exacerbations, providing interesting insights into the potential role of ...
Redwan Moqbel   +2 more
openaire   +3 more sources

Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator

Pharmaceutical Development and Technology, 2000
The purpose of this research was to evaluate the use of a rotating fluidized-bed granulator to produce acetaminophen granules with sufficient binding force between particles and good plasticity in tablets. Ethenzamide and ascorbic acid were used to compare the relationship between granulation and the sample wetness.
Kanji Fujita   +9 more
openaire   +3 more sources

Microbial communities of aerobic granules: Granulation mechanisms

Bioresource Technology, 2014
Aerobic granulation is an advanced biological wastewater treatment technology. This study for the first time identified the microbial communities of sliced samples of mature granules by polymerase chain reaction (PCR) amplification and denaturing gradient gel electrophoresis (DGGE) technique and those of whole growing granules by high-throughput ...
Duu-Jong Lee   +6 more
openaire   +3 more sources

STABILITY OF INFORMATION GRANULATION AND INFORMATION GRANULES

International Journal of Computational Intelligence and Applications, 2002
In this study, we introduce a notion of stability of information granules. Granulation of information results in a series of chunks of information usually referred to as information granules. Information granules are basic building entities involved in the formation of a broad class of systems.
George Vukovich   +2 more
openaire   +2 more sources

A study on the preparation of granules by mixer granulation

Archives of Pharmacal Research, 1979
A first systematic approach on new and simple preparation method of spherical granules in the system using organic granulating solution was carried out. Mixer granulation required narrow range of moisture content but gentle action of tumbling in the mixer and capillary forces were adequate to compact the porous mass and also were highly effective to ...
Shanghi Rhee   +3 more
openaire   +2 more sources

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