Results 131 to 140 of about 109,294 (317)
Advanced Science, EarlyView.This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li +9 more
wiley +1 more source
Advanced Science, EarlyView.We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu +8 more
wiley +1 more source
High Levels of Oxidative Stress and Skin Microbiome are Critical for Initiation and Development of Chronic Wounds in Diabetic Mice. [PDF]
, 2019 A balanced redox state is critical for proper healing. Although human chronic wounds are characterized by high levels of oxidative stress (OS), whether OS levels are critical for chronic wound development is not known.
Borneman, James +7 more
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Advanced Science, EarlyView.An AMP (P 3‐3R‐8I) based on natural peptides, which can target bacterial cell membranes, was precisely constructed via amino acid mutation. P 3‐3R‐8I exhibits antibacterial capability which could be attributed to the ability of P 3‐3R‐8I to quickly penetrate bacterial cell membranes and then to bind to bacterial DNA.
Jiaqi Huang +11 more
wiley +1 more source
The use of vacuum-assisted wound closure to enhance skin graft acceptance in a horse [PDF]
, 2011 A 16-year-old horse was admitted to the clinic of the Department of Surgery and Anesthesiology of Domestic Animals of the Faculty of Veterinary Medicine (Ghent University) for the treatment of a very large, non-healing wound extending over the ...
Jordana-Garcia, Mireia +2 more
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Advanced Science, EarlyView.Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li +8 more
wiley +1 more source
Biochemical and histological study of granulation tissue to evaluate the effect of limited access dressing in chronic wounds: A comparative study [PDF]
, 2015 Air Mshl Anil Behl +2 more
openalex +1 more source
Advanced Science, EarlyView.A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie +8 more
wiley +1 more source
Prognosis of Full-Thickness Skin Defects in Premature Infants [PDF]
Archives of Plastic Surgery, 2012 BackgroundIn the extremities of premature infants, the skin and subcutaneous tissue are very pliable due to immaturity and have a greater degree of skin laxity and mobility. Thus, we can expect wounds to heal rapidly by wound contraction.
Hyung Suk Moon +3 more
doaj
Why honey is effective as a medicine. 2. The scientific explanation of its effects [PDF]
, 2001 The effectiveness of honey as a therapeutic agent has been unequivocally demonstrated in the literature reviewed in Part 1 of this article published in 1999, but the biochemical explanation of these effects is more hypothetical.
Molan, Peter C.
core +1 more source