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Granulocyte Colony-Stimulating Factor
Southern Medical Journal, 1993Recombinant human granulocyte colony-stimulating factor (G-CSF) is a nonglycosylated protein produced in Escherichia coli using recombinant DNA technology. G-CSF was first defined in vitro as a relatively selective stimulator of pure granulocyte colonies from normal marrow and as a factor that induces differentiation of leukemic cell lines.
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Granulocyte Colony-Stimulating Factors
2004Granulocyte colony-stimulating factor (G-CSF) is a major regulator of the development of antibacterial neutrophilic granulocytic leukocytes (neutrophils). In keeping with the functions of both G-CSF and neutrophils, the murine molecule was first purified from medium that had bathed the dissected lungs of animals previously treated with a bacterial cell-
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Granulocyte colony stimulating factor.
Methods in enzymology, 1986Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
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Human granulocyte colony stimulating factor
Blut, 1987E, Platzer, J R, Kalden
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