Results 21 to 30 of about 176,387 (291)

Granulocyte Colony-Stimulating Factor [PDF]

, 2020
Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
Andrew W. Roberts, Nicos A. Nicola
openaire   +2 more sources

Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) [PDF]

, 2006
Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.
Bath, Philip M.W., Dennis, Martin S., Gray, Laura J., Russell, Nigel, Sprigg, Nikola, Walker, Marion F., Willmot, Mark, Zhao, Lian   +7 more
core   +1 more source

Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry

Haematologica, 2008
Background Information about the long-term follow-up and safety of granulocyte colony-stimulating factor administration to healthy donors is limited.
Javier de la Rubia, Felipe de Arriba, Cristina Arbona, María J. Pascual, Concha Zamora, Andrés Insunza, Dorleta Martínez, Carmen Paniagua, Miguel A. Díaz, Miguel A. Sanz   +9 more
doaj   +1 more source

Effect of filgrastim (Recombinant human granulocyte colony stimulating factor) on spatial memory in aged rats [PDF]

, 2015
Background: Apart from functioning as a multimodal hematopoietic growth factor, granulocyte colony-stimulating factor (G-CSF) causes intense consequences on the brain.
Mehrazin, E., Sepehri, H.
core   +1 more source

Failure of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in a patient with Kostmann syndrome

The Turkish Journal of Pediatrics, 1999
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar, Hakan Ongun, M. Akif Yeşilipek, Olcay Yeğin   +3 more
doaj   +1 more source

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors

FEBS Open Bio, 2022
There are two types of abnormal hematopoiesis in solid tumor occurrence and treatment: pathological hematopoiesis, and myelosuppression induced by radiotherapy and chemotherapy. In this review we primarily focus on the abnormal pathological hematopoietic
Kai He, Xi Liu, Robert D. Hoffman, Rong‐Zhen Shi, Gui‐Yuan Lv, Jian‐Li Gao   +5 more
doaj   +1 more source

Potentiation of Lupus Activity by Granulocyte Colony-Stimulating Factor

Journal of Clinical Rheumatology and Immunology, 2021
Recombinant human granulocyte colony-stimulating factor (G-CSF) is commonly used to accelerate recovery of neutropenia in patients with marrow suppression.
Tsz Ching Mok, Lok Ping Ng, Eva Tsz Fung Chui, Ho Yin Chung   +3 more
doaj   +1 more source

Neutrophil extracellular traps [PDF]

, 2013
Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-
Demers, Mélanie, Wagner, Denisa D.
core   +1 more source

Plerixafor and granulocyte colony-stimulating factor for first-line steady-state autologous peripheral blood stem cell mobilization in lymphoma and multiple myeloma: results of the prospective PREDICT trial

Haematologica, 2013
In Europe, the combination of plerixafor + granulocyte colony-stimulating factor is approved for the mobilization of hematopoietic stem cells for autologous transplantation in patients with lymphoma and myeloma whose cells mobilize poorly. The purpose of
Nigel Russell, Kenny Douglas, Anthony D. Ho, Mohamad Mohty, Kristina Carlson, G.J. Ossenkoppele, Giuseppe Milone, Macarena Ortiz Pareja, Daniel Shaheen, Arnold Willemsen, Nicky Whitaker, Christian Chabannon   +11 more
doaj   +1 more source

MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1

Haematologica, 2012
Background Mobilization of hematopoietic stem/progenitor cells from the bone marrow to the peripheral blood by granulocyte colony-stimulating factor is the primary means to acquire stem cell grafts for hematopoietic cell transplantation.
Ombretta Salvucci, Kan Jiang, Paola Gasperini, Dragan Maric, Jinfang Zhu, Shuhei Sakakibara, Georgina Espigol-Frigole, Shushang Wang, Giovanna Tosato   +8 more
doaj   +1 more source