Results 341 to 350 of about 369,640 (388)
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Decreased granulocyte response to isoproterenol in asthma during upper respiratory infections.

American Review of Respiratory Disease, 2015
Isoproterenol inhibits zymosan-stimulated release of lysosomal enzymes from granulocytes. Using this as an in vitro cell model to study beta-adrenergic response, granulocyte reaction to isoproterenol was examined in asthma.
W. Busse
semanticscholar   +1 more source

Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells.

Science, 1986
Experiments were conducted to isolate and characterize the gene and gene product of a human hematopoietic colony-stimulating factor with pluripotent biological activities.
L. Souza   +14 more
semanticscholar   +1 more source

The Neutrophilic Granulocyte

1989
The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
O. D. Laerum, H. B. Benestad
openaire   +3 more sources

Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis.

Science, 1994
The in vivo function of murine granulocyte-macrophage colony-stimulating factor (GM-CSF) was investigated in mice, carrying a null allele of the GM-CSF gene, that were generated by gene targeting techniques in embryonic stem cells.
G. Dranoff   +11 more
semanticscholar   +1 more source

Viability of frozen rat granulocytes and granulocyte precursors

Cryobiology, 1980
Abstract Mature rat polymorphonuclear leukocytes (PMNs) were frozen to −196 °C, thawed, and tested for functional viability using a variety of criteria. The assays for functional viability included: qualitative and quantitative nitroblue tetrazolium tests for phagocytic activity, fluorometric tests for membrane integrity, chemotaxis, and bactericidal
openaire   +3 more sources

Granulocyte Transfusions for Children with Infection and Neutropenia or Granulocyte Dysfunction

Pediatric Hematology and Oncology, 2014
Transfusions of granulocytes can be used as an adjunct therapy to antimicrobials in patients with infection and neutropenia or granulocyte dysfunction. However, there is a lack of strong clinical evidence to support the use of this treatment strategy, particularly in children.
Shiu-Ki Rocky Hui   +5 more
openaire   +3 more sources

A Hybrid Eosinophilic–Basophilic Granulocyte in Chronic Granulocytic Leukemia

American Journal of Clinical Pathology, 1987
Morphologic observation of the peripheral blood smear from a patient with chronic granulocytic leukemia suggested the presence of eosinophilic and basophilic granules in the same individual granulocyte. To unambiguously identify eosinophilic and basophilic granules simultaneously in the same preparation, the authors developed a cytochemical staining ...
Mary Ann Hrisinko, Susan C. Weil
openaire   +3 more sources

Granulocytic Sarcoma of the Spine

Neurosurgery, 2000
Granulocytic sarcomas (chloromas) are tumors consisting of primitive myeloid cells. They are rare manifestations of acute and chronic leukemias and can occasionally precede the development of systemic disease by weeks to years. Spinal complications of chloromas, such as cord compression secondary to epidural tumor or cauda equina syndrome, have been ...
Peter J. Lennarson   +2 more
openaire   +3 more sources

Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplantation.

New England Journal of Medicine, 1988
Recombinant human granulocyte-macrophage colony-stimulating factor (rHuGM-CSF) has been reported to increase the leukocyte count in subhuman primates subjected to total-body irradiation and in patients with the acquired immunodeficiency syndrome.
S. Brandt   +9 more
semanticscholar   +1 more source

Granulocyte Function in Untreated Acute and Chronic Granulocytic Leukemia

Acta Haematologica, 1976
Untreated patients with acute granulocytic leukemia showed impairment of microbicidal activity and,, in one, this was associated with myeloperoxidase deficiency and staphylococcal infection. In chronic granulocytic leukemia, there was no significant impairment of microbial killing.
P. H. Pinkerton, Jean B. Robinson
openaire   +3 more sources

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