Results 161 to 170 of about 101,610 (217)

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Granulocyte colony-stimulating factor protects against acute systemic alphavirus disease in a type I IFN-dependent manner. [PDF]

Front Immunol
Hameed M, Rai P, Hossain MS, Daamen A, Lipsky PE, Weger-Lucarelli J.   +5 more
europepmc   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source

Simultaneous treatment with carbimazole and granulocyte-colony stimulating factor in a patient with thyrotoxicosis and carbimazole induced neutropenia

Open Medicine, 2006
Talapatra Indrajit, Nagareddy Vengal, Bhavnani Manju, Tymms David   +3 more
doaj   +1 more source

Effects of different granulocyte colony stimulating factor regimens on patients with euploid embryo transfer in recurrent implantation failure. [PDF]

Front Med (Lausanne)
Karaosmanoglu O, Yuceturk A, Aslan IO, Yildirim Kopuk S, Utkan Korun ZE, Cakiroglu Y, Tiras B.   +6 more
europepmc   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Literature review analysis of aortitis induced by granulocyte-colony stimulating factor. [PDF]

Front Pharmacol
Zhao T, Xu H.
europepmc   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Polyethylene glycol-conjugated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) primary prophylaxis significantly reduces the duration of neutropenia in non-Hodgkin's lymphoma patients treated with chemotherapy: a randomised trial (NCT05834751). [PDF]

Transl Cancer Res
Wang B, Cao L, Li J, Zhao Y, Li J, Wen Y, Yan P, Guo W, Bai O.   +8 more
europepmc   +1 more source

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source