Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin. [PDF]
Song J+9 more
europepmc +1 more source
Immune Characterization of a Vietnamese Cohort With Idiopathic Inflammatory Myopathies
ABSTRACT Introduction/Aims Idiopathic inflammatory myopathies (IIMs) are classified into five subtypes that are associated with distinct groups of myositis‐specific antibodies (MSAs). Variations in the prevalence, genetic predisposition and clinical manifestations exist in patients with IIM from different ethnic backgrounds.
Yue‐Bei Luo+8 more
wiley +1 more source
Immune-based strategies for the treatment of biofilm infections. [PDF]
Van Roy Z, Kielian T.
europepmc +1 more source
ABSTRACT Objectives Pediatric cancer patients undergoing allogeneic hematopoietic stem cell transplantation (allo‐HSCT) are severely immunosuppressed leading to a high risk for life‐threatening infections. This trial investigates the effects of exercise during allo‐HSCT on immune cell recovery and patient‐related outcomes (DRKS00019865). Methods Twenty‐
Ronja Beller+7 more
wiley +1 more source
A Mendelian randomization study: causal relationship between immune cells and the risks of social phobia, specific phobia, and agoraphobia. [PDF]
Wang JN+8 more
europepmc +1 more source
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre+5 more
wiley +1 more source
Deuterated water (<sup>2</sup>H<sub>2</sub>O, heavy water) labelling to investigate human cell dynamics <i>in vivo</i> - lessons in protocol design and toxicity from the current literature. [PDF]
Song A+4 more
europepmc +1 more source
Tutorial for Modeling Delays in Biological Systems in the NONMEM Software
ABSTRACT Delays in biological systems are a common phenomenon. The models for delays require specialized mathematical and numerical techniques such as transit compartments, delay differential equations (DDEs), and distributed DDEs (DDDEs). Because of mathematical complexity, DDEs and particularly DDDEs are infrequently used for modeling.
Robert J. Bauer, Wojciech Krzyzanski
wiley +1 more source
Associations between inflammation and striatal dopamine D2-receptor availability in aging. [PDF]
Crine V+10 more
europepmc +1 more source
Potential roles of antibodies with different classes in IgG4‐related diseases
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li+6 more
wiley +1 more source