This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley +1 more source
Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis. [PDF]
Lyu X+7 more
europepmc +1 more source
ABSTRACT Background In Europe, pembrolizumab with or without chemotherapy is the recommended first‐line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), with a combined positive score (CPS) ≥ 1. In France, the TPExtreme (TPEx) regimen is preferred for CPS < 1.
Alizée Simon+6 more
wiley +1 more source
Immune Thrombocytopenia in a 94-Year-Old Woman: Challenges in Diagnosis and Management of an Uncommon Presentation in the Elderly. [PDF]
Thornburgh K, Faust TF, Horton TL.
europepmc +1 more source
The role of KLF4 in phagocyte activation during infectious diseases. [PDF]
Herta T+3 more
europepmc +1 more source
Detection of autoantibodies against exocrine pancreas by double immunodiffusion testing [PDF]
Horbach, E.+5 more
core
Cerebrospinal Fluid Cytology in Lyme Neuroborreliosis Revisited-Role of Neutrophilic Granulocytes: A Retrospective Single-Center Study. [PDF]
Otto F+5 more
europepmc +1 more source
Functional Interactions Between Recombinant Serum Amyloid A1 (SAA1) and Chemokines in Leukocyte Recruitment. [PDF]
Van Damme J+4 more
europepmc +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner+3 more
wiley +1 more source