Results 111 to 120 of about 63,225 (201)

A reaction-diffusion model for Mycobacterium tuberculosis infection [PDF]

arXiv
This paper aims to investigate a reaction-diffusion model which describes in-host infection for Mycobacterium tuberculosis (Mtb) allowing random motion (i.e. linear diffusion) and chemotaxis (i.e. non-linear diffusion) of macrophages and bacteria populations.
arxiv  

Gravidarum granuloma associated to an osseointegrated implant: case report

Revista de Odontologia da UNESP
Introduction: Pyogenic granuloma, known as gravidarum granuloma or pregnancy granuloma, is a benign non-neoplastic reactive oral lesion that may occur in pregnant women.
Cleverson Luciano Trento, Vanessa Cristina Veltrini, Rivelino Nímio Marques dos Santos, Vanessa Tavares de Gois Santos   +3 more
doaj   +1 more source

EXACT-CT: EXplainable Analysis for Crohn's and Tuberculosis using CT [PDF]

arXiv
Crohn's disease and intestinal tuberculosis share many overlapping features such as clinical, radiological, endoscopic, and histological features - particularly granulomas, making it challenging to clinically differentiate them. Our research leverages 3D CTE scans, computer vision, and machine learning to improve this differentiation to avoid harmful ...
arxiv  

Endomyocardial biopsy in the diagnosis of cardiac sarcoidosis

European Journal of Heart Failure, Volume 27, Issue 3, Page 488-497, March 2025.
The diagnostic performance of endomyocardial biopsy (EMB) in 216 patients with cardiac sarcoidosis (CS). The overall sensitivity of the first EMB was 38%, although it varied markedly depending on the extent and severity of the disease. Major complications were rare (<1%) and no deaths or permanent sequels were observed.
Henriikka Mälkönen, Jukka Lehtonen, Pauli Pöyhönen, Valtteri Uusitalo, Mikko I. Mäyränpää, Markku Kupari   +5 more
wiley   +1 more source

Understanding Sarcoidosis Using Large Language Models and Social Media Data [PDF]

Journal of Healthcare Informatics Research, 2024
Sarcoidosis is a rare inflammatory disease characterized by the formation of granulomas in various organs. The disease presents diagnostic and treatment challenges due to its diverse manifestations and unpredictable nature. In this study, we employed a Large Language Model (LLM) to analyze sarcoidosis-related discussions on the social media platform ...
arxiv  

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Advancing Chronic Tuberculosis Diagnostics Using Vision-Language Models: A Multi modal Framework for Precision Analysis [PDF]

arXiv
Background: This study proposes a Vision-Language Model (VLM) leveraging the SIGLIP encoder and Gemma-3b transformer decoder to enhance automated chronic tuberculosis (TB) screening. By integrating chest X-ray images with clinical data, the model addresses the challenges of manual interpretation, improving diagnostic consistency and accessibility ...
arxiv  

Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma

Cancer Communications, Volume 45, Issue 5, Page 494-499, May 2025.
Jia Xiang Jin, Fabia Fuchslocher, Martha Carreno‐Gonzalez, Felina Zahnow, A. Katharina Ceranski, Rainer Will, Dominic Helm, Felix Bestvater, Ana Banito, Roland Imle, Shunya Ohmura, Florencia Cidre‐Aranaz, Thomas G. P. Grünewald   +12 more
wiley   +1 more source

VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection

Cell Reports, 2019
Summary: Many autoimmune and infectious diseases are characterized by the formation of granulomas which are inflammatory lesions that consist of spatially organized immune cells.
Jeffrey S. Harding, Melinda Herbath, Yuli Chen, Aditya Rayasam, Anna Ritter, Balazs Csoka, George Hasko, Iacovos P. Michael, Zsuzsanna Fabry, Andras Nagy, Matyas Sandor   +10 more
doaj  

Sarcoid‐Like Reaction (SLR) Associated With Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 8, Issue 3, Page 285-288, May 2025.
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) are useful in the treatment of metastatic renal cell carcinoma. ICIs have been associated with a variety of immune‐related adverse events (irAEs), one of which is a sarcoid‐like reaction (SLR). SLR is often difficult to distinguish from cancer progression.
Kanta Fukushima, Sota Mizukoshi, Tomohiro Ino, Takuya Ishida, Yumika Ito, Akira Okimura, Munehide Nakatsugawa, Takeshi Hashimoto   +7 more
wiley   +1 more source