Results 1 to 10 of about 72,768 (120)

Neutropenic fever of unknown origin and disseminated granulomatous disease in a patient with acute lymphoblastic leukemia. [PDF]

Rev Fac Cien Med Univ Nac Cordoba, 2022
An 18-year-old male was admitted for his second induction chemotherapy treatment for an acute lymphoblastic leukaemia with cyclophosphamide, cytarabine, and mercaptopurine.
Santarelli IM, Manzella PO, Ingold JJ, Legnoverde S, Falcón MF, Fernández SI, Melero MJ.   +6 more
europepmc   +3 more sources

The immunoregulatory landscape of human tuberculosis granulomas

Nature Immunology, 2022
Tuberculosis (TB) in humans is characterized by formation of immune-rich granulomas in infected tissues, the architecture and composition of which are thought to affect disease outcome. However, our understanding of the spatial relationships that control
Erin F Mccaffrey, Michele Donato, Leeat Keren   +2 more
exaly   +2 more sources

Sarcoidose [PDF]

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2016
A sarcoidose consiste numa doença inflamatória multissistémica, de etiologia desconhecida, que se caracteriza pela formação de granulomas não-caseosos nos órgãos envolvidos, predominantemente pulmões e gânglios intratorácicos.
Sara Castelo Branco, Karin Luz, Cândida Fernandes, Jorge Cardoso   +3 more
doaj   +3 more sources

Sarcoidose pulmonar: achados na tomografia computadorizada de alta resolução Pulmonary sarcoidosis: high-resolution computed tomography findings

Jornal Brasileiro de Pneumologia, 2005
A sarcoidose é uma doença sistêmica de causa indeterminada, caracterizada por granulomas não-caseosos. Embora possa afetar qualquer órgão, esta doença tem sua morbi-mortalidade relacionada principalmente ao acometimento pulmonar, presente em 80% a 90 ...
Bruno Barcelos da Nóbrega, Gustavo de Souza Portes Meirelles, Gilberto Szarf, Dany Jasinowodolinski, Jorge Issamu Kavakama   +4 more
doaj   +2 more sources

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

ACS Nano, 2018
The enhanced permeability and retention (EPR) effect is the only described mechanism enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting mechanism.
Federico Fenaroli, Yitian Xu, Simon Van Herck   +2 more
exaly   +2 more sources

Inflammatory signaling in human tuberculosis granulomas is spatially organized

Nature Medicine, 2016
Granulomas are the pathological hallmark of tuberculosis (TB). However, their function and mechanisms of formation remain poorly understood. To understand the role of granulomas in TB, we analyzed the proteomes of granulomas from subjects with ...
Mohlopheni Jackson Marakalala, Ravikiran M Raju, Eliseo A Eugenin   +2 more
exaly   +2 more sources

Differentiation of periapical granulomas and cysts by using dental MRI: a pilot study

International Journal of Oral Science, 2018
The purpose of this pilot study was to evaluate whether periapical granulomas can be differentiated from periapical cysts in vivo by using dental magnetic resonance imaging (MRI).
Alexander Heil, Martin Bendszus, Sabine Heiland   +2 more
exaly   +2 more sources

Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

Mucosal Immunology, 2019
Neutrophils are implicated in the pathogenesis of tuberculosis (TB), a disease caused by Mycobacterium tuberculosis infection, but the mechanisms by which they promote disease are not fully understood.
Joshua T Mattila
exaly   +2 more sources

An explant technique for high-resolution imaging and manipulation of mycobacterial granulomas

Nature Methods, 2018
A central and critical structure in tuberculosis, the mycobacterial granuloma consists of highly organized immune cells, including macrophages that drive granuloma formation through a characteristic epithelioid transformation.
Mark R Cronan, Molly A Matty, Landry Blanc   +2 more
exaly   +2 more sources

Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques

Mucosal Immunology, 2017
Protection against Mycobacterium tuberculosis (Mtb) infection requires CD4 T cells to migrate into the lung and interact with infected macrophages. In mice, less-differentiated CXCR3+ CD4 T cells migrate into the lung and suppress growth of Mtb, whereas ...
Keith D Kauffman, Michelle A Sallin, Shunsuke Sakai, Olena Kamenyeva, J. Kabat, Danielle M. Weiner, M. Sutphin, D. Schimel, L. Via, C. Barry, Temeri Wilder-Kofie, Ian N. Moore, Rashida Moore, Daniel L. Barber   +13 more
exaly   +2 more sources