Results 91 to 100 of about 21,257 (220)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

CLINICAL AND RADIOLOGICAL CHARACTERISTICS OF ANCA-ASSOCIATED VASCULITIS: 7 YEARS OF EXPERIENCE IN DIAGNOSIS AND TREATMENT

Сибирский научный медицинский журнал, 2020
The aim of the research is to study nosological structure, features of kidney, lung damage, deaths in patients with ANCA – associated vasculitis underwent medical treatment in a multidisciplinary hospital. Material and methods.
L. M. Kudelya, Ya. L. Manakova, E. S. Khusainova, E. A. Drobyazgin, A. V. Kutepov, A. M. Gorbovskaya, A. V. Korobeynikov, L. A. Bogoderova, I. A. Zubritskaya, V. F. Khusainov, K. I. Shcherbina   +10 more
doaj   +1 more source

Granulomatosis with polyangiitis mimicking infective endocarditis in an adolescent male [PDF]

, 2016
Granulomatosis with polyangiitis (GPA) is a rare but serious small vessel vasculitis with heterogeneous clinical presentation ranging from mainly localised disease with a chronic course, to a florid, acute small vessel vasculitic form characterised by ...
Brogan, PA, Christov, G, Eleftheriou, D, Sebire, N, Varnier, GC   +4 more
core   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

Journal of Allergy and Clinical Immunology: Global
This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting ...
Sonia Iqbal, DO, Joseph A. Baxter, DO, Karla E. Adams, MD   +2 more
doaj   +1 more source

Oral Angiolymphoid Hyperplasia With Eosinophilia Exhibiting Cutaneous‐Type Histopathologic Features: Clinical Regression Following Hormonal Withdrawal and a 50‐Year Review

Journal of Cutaneous Pathology, EarlyView.
Case report of a 30‐year‐old female. Asymptomatic, red‐purple hyperplastic lesion extending from teeth 21 to 25, with bleeding upon manipulation. Differential diagnosis included: inflammatory gingival hyperplasia, plasma cell gingivitis, leukemia, and Wegener's granulomatosis.
Pedro Vinícius Santos de Jesus, Louise Cristina Santos, Gilberth Tadeu Dos Santos Aciole, John Lennon Silva Cunha, Nicole Lonni, Matheus Antoni da Silva Costa, Elena Riet Correa Rivero, Rogério Gondak, Ricardo Luíz Cavalcanti de Albuquerque‐Júnior   +8 more
wiley   +1 more source

Linked help from bacterial proteins drives autoantibody production in small vessel vasculitis. [PDF]

, 2018
The small vessel vasculitides granulomatosis with polyangiitis (GPA) and microscopic polyangiitis are associated with autoantibodies to neutrophil cytoplasm antigens (ANCA), principally proteinase-3 (PR3) and myeloperoxidase (MPO).
Oliveira, DBG
core   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA). [PDF]

, 2013
INTRODUCTION: The present study aimed to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis (GPA).
Abdulahad, WH, Doornbos-van der Meer, B, Heeringa, P, Huitema, MG, Kallenberg, CGM, Lepse, N, Limburg, PC, Rutgers, A, Stegeman, CA, Tadema, H   +9 more
core   +3 more sources

Oral granulomatosis with polyangiitis

Journal of Dental Sciences, 2023
Tsai, Chen-Hsi, Chen, Yuk-Kwan, Chen, Yu Feng, Tseng, Chih-Huang   +3 more
openaire   +2 more sources