Results 91 to 100 of about 64,510,463 (206)

Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit

The Laryngoscope, Volume 136, Issue 9, Page 3980-3989, September 2026.
This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann, David Oestreicher, Marc Albert Hüser, Dirk Beutner, Christian Wrobel   +4 more
wiley   +1 more source

METTL7A‐Dependent m6A Methylation Orchestrates CXCR4hi Neutrophil Pathogenicity and NETosis in Skin Inflammation

MedComm, Volume 7, Issue 9, September 2026.
In psoriasis, METTL7A is upregulated in aged CXCR4hi neutrophils, where it stabilizes PLSCR1 mRNA via m6A modification to enhance reactive oxygen species (ROS) production and neutrophil extracellular trap (NET) formation, thereby exacerbating disease severity.
Wanting Liu, Jinkai Liang, Huiyi Quan, Xuan Liu, Kang Li, Xin Tang, Jiaqi Wang, Yunfeng Gu, Yaxing Bai, Ke Xue, Zhiguo Li, Xiaolei Su, Erle Dang, Jiaoling Chen, Gang Wang, Shuai Shao   +15 more
wiley   +1 more source

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

Journal of Allergy and Clinical Immunology: Global
This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting ...
Sonia Iqbal, DO, Joseph A. Baxter, DO, Karla E. Adams, MD   +2 more
doaj   +1 more source

Macula Retinal Vasculitis and Choroiditis Associated With Granulomatosis With Polyangiitis

, 2017
Purpose:To report a case series of two cases of granulomatosis with polyangiitis, previously known as Wegener granulomatosis, which developed macular necrosis, not previously associated with granulomatosis with polyangiitis, healed with fibrosis, despite
Vinaya Vasudevan, Albert T. Vitale, Vasudevan, Vinaya, Shelton, Julie, Julie Shelton, Vitale, Albert T., Moorthy, Ramana S N, Shelton, Julie B., Lim, Lik Thai, Lik Thai Lim, Moorthy, Ramana, Ramana Moorthy   +11 more
core   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, Volume 81, Issue 9, Page 3171-3184, September 2026.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

Allergy, Volume 81, Issue 9, Page 3146-3156, September 2026.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani   +22 more
wiley   +1 more source

Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali, Nidhi Agrawal, Smeeta Sinha, Dimitrios Poulikakos, Jamil Choudhury, Constantina Chrysochou   +5 more
wiley   +1 more source

Place in therapy of rituximab in the treatment of granulomatosis with polyangiitis and microscopic polyangiitis

, 2015
Shivani Shah, Duvuru Geetha Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Granulomatosis with polyangiitis and microscopic polyangiitis are small vessel vasculitides ...
Shah S, Geetha D
core  

Nomenclature and classification of vasculitis: lessons learned from granulomatosis with polyangiitis (Wegener's granulomatosis): Nomenclature, Classification of vasculitis [PDF]

, 2011
Names influence how something is perceived. Diagnostic terms (diagnoses) are the names of diseases that are usually derived either from some distinctive characteristic of the disease or include an eponym recognizing someone who elucidated the disease. No
Jennette, J.C.
core   +1 more source

A variety of clinical presentations of eosinophilic granulomatosis with polyangiitis: a comprehensive review

Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by eosinophilic granulomatous vasculitis. Typical symptoms include late-onset bronchial asthma and blood and tissue eosinophilia.
Agata Sebastian, Joanna Kosałka-Węgiel
core   +1 more source