Results 61 to 70 of about 30,079 (265)

The Role of T Helper Type 2 (Th2) Cytokines in the Pathogenesis of Eosinophilic Granulomatosis with Polyangiitis (eGPA): an Illustrative Case and Discussion

Current Allergy and Asthma Reports, 2022
The pathogenesis of eosinophilic granulomatosis with polyangiitis (eGPA) is driven largely by CD4 + type 2 helper T cells (Th2), B cells, and eosinophils.
M. Milne, Jack Kimball, T. Tarrant, R. Al-Rohil, David L. Leverenz   +4 more
semanticscholar   +1 more source

Difficulties in diagnosis of granulomatosis with polyangiitis in a child with concomitant pulmonary aspergillosis

Актуальные проблемы теоретической и клинической медицины
Granulomatosis with polyangiitis, formerly known as Wegener's granulomatosis, is an autoimmune antineutrophil cytoplasmic antibodies – associated systemic vasculitis with a progressive course.Granulomatosis with polyangiitis remains one of the most ...
M. A. Borodin, D. B. Ismailova, S. H. Ispulaeva   +2 more
doaj   +1 more source

A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fcγ-RIIa Genes

Kidney & Blood Pressure Research, 2013
Background/Aims: The aim of the study is to search for associations between Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and polymorphisms in the genes of four key molecules possibly involved in different pathogenic pathways ...
Ulf Persson, Birgitta Gullstrand, Åsa Pettersson, Gunnar Sturfelt, Lennart Truedsson, Mårten Segelmark   +5 more
doaj   +1 more source

Granulomаtosis With Polyangiitis Affecting the Lung and Orbit

Вестник рентгенологии и радиологии, 2021
The paper describes a clinical case of pulmonary and right orbital injuries in granulomatosis with polyangiitis in a 38-year-old male. The case is of considerable interest due to the rarity of this pathology, especially because of the localization in the
Zh. V. Sheikh, I. E. Tyurin, T. D. Safonova, A. M. Andreychenko   +3 more
doaj   +1 more source

Novel insights into the aetiology of granulomatosis with polyangiitis—a case–control study using the Clinical Practice Research Datalink [PDF]

, 2018
Objectives We aimed to provide insights into the aetiology of granulomatosis with polyangiitis (GPA), by conducting a large case–control study using a general population-based, prospectively collected database of healthcare records.
Abhishek Abhishek, Benchimol, Benucci, Bonatti, Burn, Chung, Cooper, CPRD, Cárdenas-Roldán, Dave, de Lind van Wijngaarden, Derrett-Smith, Dhasmana, Draibe, Fiona A Pearce, Guellec, Haubitz, Herrett, Herrett, Hollowell, Issoufaly, Lewis, Lhote, Lionaki, Mahadeva, Mahid, Mahr, Maier, Matsuyama, Matthew J Grainge, Matzaraki, Mooney, Neel, NHS Digital, NHS Digital, O’Donnell, Pagnoux, Pearce, Peter C Lanyon, Peters, Popa, Reumaux, Richard A Watts, Richard B Hubbard, Scalapino, Somers, Sopori, Springate, Suppiah, Takahashi, Vaidya, Von Elm, Watts, Wilczynska   +53 more
core   +2 more sources

Types of Angiopathy in Experimental Autoimmune Disease in Rats [PDF]

, 2017
The purpose and objectives of this work were to study the nature of the heart, lungs and kidneys angiopathy in rats with a model of systemic autoimmune disease, carrying out comparisons of the results with extravasal morphological manifestations of the ...
Iegudina, Y. (Yelizaveta), Mikuksts, V. (Viktoriya), Syniachenko, O. (Oleg), Yakovlenko, P. (Pavel)   +3 more
core   +2 more sources

Granulomatosis With Polyangiitis Presenting With Diffuse Alveolar Hemorrhage: A Systematic Review

Cureus, 2022
Granulomatosis with polyangiitis (GPA) is a systemic disease that has variable clinical expression. GPA is the most common antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
R. C. da Silva, P. Adhikari
semanticscholar   +1 more source

Risk factors and treatment of pneumothorax secondary to granulomatosis with polyangiitis: a clinical analysis of 25 cases

Journal of Cardiothoracic Surgery, 2018
Objectives To investigate the risk factors and treatment strategies for pneumothorax secondary to granulomatosis with polyangiitis (GPA). Method Retrospective analysis of cases with pneumothorax secondary to GPA from our own practice and published on ...
Xuhua Shi, Yongfeng Zhang, Yuewu Lu
doaj   +1 more source

Linked help from bacterial proteins drives autoantibody production in small vessel vasculitis. [PDF]

, 2018
The small vessel vasculitides granulomatosis with polyangiitis (GPA) and microscopic polyangiitis are associated with autoantibodies to neutrophil cytoplasm antigens (ANCA), principally proteinase-3 (PR3) and myeloperoxidase (MPO).
Oliveira, DBG
core   +1 more source

Pyoderma Gangrenosum-like Ulcers Associated Granulomatosis with Polyangiitis

Case Reports in Clinical Practice
Granulomatosis with polyangiitis is an ANCA-positive vasculitis primarily affecting small to medium-sized vessels, typically involving the lungs and kidneys.
Katia Fabiola Avila, Karla López López, María del Coral Durand Muñoz, Judith Guadalupe Domínguez Cherit   +3 more
doaj   +1 more source