Background: Balamuthia mandrillaris is a free-living amoebic agent affecting the central nervous system or skin with a 95% mortality rate, eventually manifesting as granulomatous amoebic encephalitis (GAE) or meningoencephalitis in both immunocompetent ...
Italia, Yukta, Luke, Rebecca
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Naegleria fowleri, Balamuthia mandrillaris and Acanthamoeba spp. are free-living amoebae which rarely cause human infections. N. fowleri induces primary amoebic meningoencephalitis mostly among children and young adults. B.
Štofaniková, Petra
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Encephalitis caused by Free-living amoebae (FLA) has a mortality rate of around 95-98%, a fraction that has not changed in the past decades. Pathogenic FLA include Acanthamoeba, Balamuthia mandrillaris, and Naegleria fowleri that are known to target the ...
Baig, Abdul Mannan
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Fatal granulomatous amoebic encephalitis due to Acanthamoeba sp. with bacterial co-infection in an immunocompetent critically ill patient: A case report and review of the literature. [PDF]
Boukoub N +5 more
europepmc +1 more source
Free-living amoebae: Pathogens and the central nervous system (CNS) disease
Pathogenic free-living amoebae are known to be the causative agents of central nervous system infections leading to fatal primary amoebic meningoencephalitis or granulomatous amoebic encephalitis.
Mungroo, Mohammad Ridwane +2 more
core +1 more source
A unified digital twin framework for predicting therapeutic response to central nervous system infections by pathogenic free-living amoebae. [PDF]
Siddiqui R +3 more
europepmc +1 more source
Interaction between host and pathogenic amoeba Acanthamoeba castellanii
Acanthamoeba castellanii is a free-living protozoa that can cause serious human illnesses. These illnesses include Acanthamoeba keratitis and granulomatous Acanthamoeba encephalitis.
Klosse, Victoria
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We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis.
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Disseminated Acanthamoeba Infection with Necrotic Skin Lesions and Granulomatous Vasculitis, United States. [PDF]
Koshy M +5 more
europepmc +1 more source
Integrating Molecular Pathogenesis and Host Response into a Digital Twin Framework for Predicting Therapeutic Outcomes in <i>Balamuthia mandrillaris</i> Encephalitis. [PDF]
Siddiqui R, Maciver SK, Khan NA.
europepmc +1 more source

