Results 151 to 160 of about 1,345 (177)

Combined drug therapy in the management of granulomatous amoebic encephalitis due to Acanthamoeba spp., and Balamuthia mandrillaris

open access: yesExperimental Parasitology, 2014
Granulomatous amoebic encephalitis (GAE) is caused by two protist pathogens, Acanthamoeba spp., and Balamuthia mandrillaris. Although rare, it almost always results in death. In the present study, amoebae were treated with various combinations of clinically-approved drugs, targeting vital cellular receptors and biochemical pathways.
Abdul Mannan Baig   +2 more
exaly   +4 more sources

A Case of Granulomatous Amoebic Encephalitis diagnosed and intervened at an Early Stage

open access: yesJapanese Journal of Neurosurgery, 2023
Tomoya Ogawa   +2 more
exaly   +2 more sources

Successful Treatment of Granulomatous Amoebic Encephalitis with Combination Antimicrobial Therapy

open access: yesInternal Medicine, 2013
Granulomatous amoebic encephalitis (GAE) is a rare but fatal infection. Due to its nonspecific symptoms and laboratory and neuroradiological findings, it is rarely diagnosed antemortem. We herein present the case of a 72-year-old Japanese woman who was diagnosed with GAE following the detection of a pathogen similar to Balamuthia mandrillaris under a ...
Hiroyuki Yuasa, Tatsuru Hara
exaly   +4 more sources

Granulomatous amoebic encephalitis presenting as a solitary mass lesion

open access: yesRadiology of Infectious Diseases, 2020
Abstract Granulomatous amoebic encephalitis is a rare progressive infectious disease of the central nervous system with a high mortality rate. It usually presents as multiple ring-enhancing lesions in the brain with surrounding edema evident, while the granulomatous amoeba encephalitis reported in this case is manifested as a solitary mass in the ...
Nian Xia Fu
exaly   +2 more sources

Granulomatous Amoebic Encephalitis Caused by Balamuthia Mandrillaris in an Immunocompetent Girl

World Neurosurgery, 2012
Balamuthia mandrillaris is a recently recognized cause of a rare, devastating infection, granulomatous amoebic encephalitis (GAE). Presenting symptoms of GAE are nonspecific and can last for months before becoming clinically significant. Once the infection involves the central nervous system, death often results within days to weeks.
Martin E Weinand
exaly   +3 more sources

Granulomatous amoebic encephalitis caused byAcanthamoeba in a patient with systemic lupus erythematosus

Clinical Rheumatology, 1998
A 25-year-old chronically immunosuppressed woman with systemic lupus erythematosus (SLE) died after developing subacute granulomatous encephalitis caused by Acanthamoeba. Amoebic trophozoites were also found in the lung, suggesting a primary pulmonary focus of infection.
J Koide, Tsutomu Takeuchi, Mori S
exaly   +3 more sources

Imaging monitoring of Balamuthia granulomatous amoebic encephalitis

Clinical Neurology and Neurosurgery
Balamuthia granulomatous amoebic encephalitis (GAE) is a rare and highly lethal infectious disease affecting the central nervous system, caused by the Balamuthia amoeba. This article reports the case of a child with normal immune function and no apparent epidemiological risk factors.
Chenmei Zhang
exaly   +3 more sources

Balamuthia mandrillaris Granulomatous Amoebic Encephalitis: The First African Experience

Journal of the Pediatric Infectious Diseases Society, 2022
Abstract We report the first case of Balamuthia mandrillaris granulomatous amoebic encephalitis definitively acquired in Africa. Our case emphasizes initial nonspecific dermatological features, delays in confirmation of the diagnosis, difficulties accessing recommended medication, and uncertainty about optimal treatment of a disease with
Hafsah D Tootla   +9 more
openaire   +2 more sources

Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris

Medical Journal of Australia, 1997
Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is rare (63 human) cases reported worldwide) and fatal. We report a case in a five-year-old boy who had previously been well. For 18 months, he had had a slowly progressive, granulomatous mid facial lesion, but despite extensive investigation definitive diagnosis was made only with ...
Reed, R.P.   +6 more
openaire   +4 more sources

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