Results 61 to 70 of about 89,859 (293)

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

Chronic Crohn’s disease: diagnosis and management at the present times

Zdorovʹe Rebenka, 2018
The article deals with the data on the prevalence, diagnosis, treatment, prevention of bacterial and fungal infections in children with chronic granulomatous disease.
V.A. Klimenko, O.V. Piontkovska, O.S. Lupaltseva, T.O. Khalturina, O.M. Savvo, N.I. Timokhina, G.M. Soboleva   +6 more
doaj   +1 more source

COVID-19 in Chronic Granulomatosis Disease: A Case Report

Iranian Journal of Allergy, Asthma and Immunology, 2022
A novel coronavirus disease known as Coronavirus Disease 2019 (COVID-19) has spread quickly throughout the world, and it was declared a pandemic in March 2022.
Hossein Esmaeilzadeh, Seyed Sina Dehghani, Babak Shahhoseini, Soheila Alyasin, Sayyed Hesamedin Nabavizadeh, Aida Askari   +5 more
doaj   +1 more source

Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children [PDF]

, 2017
AW and JK are supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of AberdeenPeer reviewedPublisher ...
King, Jill, Lehrnbecher, Thomas, Pana, Zoi-Dorothea, Steinbach, William J., Warris, Adilia   +4 more
core   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

A Case of Chronic Granulomatous Disease with a Necrotic Mass in the Bronchus: A Case Report and a Review of Literature

Case Reports in Pulmonology, 2012
Chronic granulomatous disease is a rare phagocytic disorder with recurrent, severe bacterial and fungal infections. We describe an unusual case of chronic granulomatous disease manifesting as an invasive pulmonary aspergillosis with an obstructive ...
Ali Cheraghvandi, Majid Marjani, Saeid Fallah Tafti, Logman Cheraghvandi, Davoud Mansouri   +4 more
doaj   +1 more source

Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate

American Journal of Industrial Medicine, EarlyView.
ABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Guilherme Ward Leite, Eduardo Kaiser Ururahy Nunes Fonseca, Rodrigo Caruso Chate, Lavinia Clara Del Roio, Sofia de Paiva Memento Machado, Jefferson Benedito de Freitas, Ronaldo Adib Kairalla, Mário Terra‐Filho, Ubiratan Paula Santos, Rafael Futoshi Mizutani   +9 more
wiley   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Severe Occupational Hypersensitivity Pneumonitis: A Case Series of Four Patients Requiring Lung Transplantation

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease triggered by repeated inhalation of organic or chemical antigens. Occupational exposures account for approximately 19% of all cases. Early diagnosis, identification of the responsible antigen(s), and immediate avoidance of exposure are crucial to prevent ...
Ludwig Frei‐Stuber, Judith Mohren, Ester Mau, Bernhard Werner, Rudolf A. Hatz, Jürgen Barton, Dennis Nowak   +6 more
wiley   +1 more source

A histopathologic evaluation of gross lesions excised from commercially important North Altantic marine fishes [PDF]

, 1986
Histopathologic studies of lesions found in commercially important North Atlantic marine fishes are uncommon. As part of a comprehensive Northeast Fisheries Center program ("Ocean Pulse") to evaluate environmental and resource health on the U.S ...
Despres-Patanjo, Linda, Murchelano, Robert A., Ziskowski, John   +2 more
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