Results 61 to 70 of about 89,434 (295)

COVID-19 in Chronic Granulomatosis Disease: A Case Report

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2022
A novel coronavirus disease known as Coronavirus Disease 2019 (COVID-19) has spread quickly throughout the world, and it was declared a pandemic in March 2022.
Hossein Esmaeilzadeh   +5 more
doaj   +1 more source

A Review of Chronic Granulomatous Disease [PDF]

open access: yesAdvances in Therapy, 2017
Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defects in any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst in phagocytic leukocytes. Patients with CGD are at increased risk of life-threatening infections with catalase-positive bacteria and fungi and inflammatory complications such ...
Arnold, Danielle E.   +1 more
openaire   +2 more sources

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang   +16 more
wiley   +1 more source

A Case of Chronic Granulomatous Disease with a Necrotic Mass in the Bronchus: A Case Report and a Review of Literature

open access: yesCase Reports in Pulmonology, 2012
Chronic granulomatous disease is a rare phagocytic disorder with recurrent, severe bacterial and fungal infections. We describe an unusual case of chronic granulomatous disease manifesting as an invasive pulmonary aspergillosis with an obstructive ...
Ali Cheraghvandi   +4 more
doaj   +1 more source

Chronic Crohn’s disease: diagnosis and management at the present times

open access: yesZdorovʹe Rebenka, 2018
The article deals with the data on the prevalence, diagnosis, treatment, prevention of bacterial and fungal infections in children with chronic granulomatous disease.
V.A. Klimenko   +6 more
doaj   +1 more source

Report of results of pleural biopsy (Needle biopsy and open biopsy) in 108 cases and 245 biopsies [PDF]

open access: yes, 1960
1. The results of 245 pleural biopsies perfomed in 108 patients including 219 pleural needle biopsies and 26 pleural open biopsies were reported. The method of pleural biopsy seems to be superior to any other currently available diagnostic procedures for
Mc, Lt. Col., Sohn, Isaack
core   +1 more source

CHRONIC GRANULOMATOUS DISEASE OF CHILDHOOD [PDF]

open access: yesAmerican Journal of Roentgenology, 1968
Chronic granulomatous disease is an hereditary disease of males who have an abnormality in their defense against bacterial infections. Recently it has been shown that granulocytic leukocytes, in these patients, lack a leukocytic oxidase enzyme which is necessary for effective intracellular bacterial destruction.
W J, Caldicott, R L, Baehner
openaire   +2 more sources

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]

open access: yes, 2017
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil.  NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM   +7 more
core  

Hepatic stellate cells and parasite-induced liver fibrosis [PDF]

open access: yes, 2010
: Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT   +3 more
core   +2 more sources

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