Results 61 to 70 of about 1,240,530 (301)
Predicting Development of Chronic Obstructive Pulmonary Disease and its Risk Factor Analysis [PDF]
arXiv, 2023 Chronic Obstructive Pulmonary Disease (COPD) is an irreversible airway obstruction with a high societal burden. Although smoking is known to be the biggest risk factor, additional components need to be considered. In this study, we aim to identify COPD risk factors by applying machine learning models that integrate sociodemographic, clinical, and ...
arxiv
Journal of the Pediatric Infectious Diseases Society, 2018 Chronic granulomatous disease is a rare and potentially fatal disorder of neutrophil function. Beyond current medical management and hematopoietic stem cell transplantation, new methods of gene therapy that use lentiviral vectors or gene editing might ...
M. Keller, L. Notarangelo, H. Malech
semanticscholar +1 more source
Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy
Advanced Therapeutics, EarlyView.Tuberculosis (TB) remains a global health challenge, with drug‐resistant strains exacerbating the issue. Metallic nanoparticles (MNPs) show promise in TB diagnosis as sensor probes and in combination therapy with antimycobacterial drugs, requiring further pre‐clinical and clinical research for clinical translation.
Christianah Aarinola Akinnawo +1 more
wiley +1 more source
Chronic Crohn’s disease: diagnosis and management at the present times
Zdorovʹe Rebenka, 2018 The article deals with the data on the prevalence, diagnosis, treatment, prevention of bacterial and fungal infections in children with chronic granulomatous disease.
V.A. Klimenko +6 more
doaj +1 more source
Advanced Science, EarlyView.An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou +35 more
wiley +1 more source
Pediatric Reports, 2020 Allogeneic hematopoietic stem-cell transplantation is a well-known curative treatment for patients with chronic granulomatous disease. We present our experiment regarding ten patients with chronic granulomatous disease who underwent a reduced intensity ...
Tahereh Rostami, Azadeh Kiumarsi
doaj +1 more source
Data-driven dynamic treatment planning for chronic diseases [PDF]
arXiv, 2022 In order to deliver effective care, health management must consider the distinctive trajectories of chronic diseases. These diseases recurrently undergo acute, unstable, and stable phases, each of which requires a different treatment regimen. However, the correct identification of trajectory phases, and thus treatment regimens, is challenging.
arxiv
Blood, 2016 Chronic granulomatous disease (CGD) can be cured by allogeneic hemopoietic stem cell transplantation (HSCT). Complications include graft failure, graft-versus-host disease (GVHD), infection, and transplant-related mortality; therefore, reduced-intensity ...
B. Morillo-Gutiérrez +22 more
semanticscholar +1 more source
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Advanced Science, EarlyView.Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon +25 more
wiley +1 more source
A Rare Form of Chronic Granulomatous Disease (Type Iva) Presenting as Inflammatory Bowel Disease
Canadian Journal of Gastroenterology, 1996 Neutrophil dysfunction syndromes can sometimes mimic the clinical and pathological features of inflammatory bowel disease. The case of a 3.5-year-old boy with chronic diarrhea, abdominal pain, poor growth since infancy and microcytic, hypochromic anemia ...
Francisco A Sylvester
doaj +1 more source