Results 161 to 170 of about 91,202 (292)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Chronic granulomatous disease: Clinical, microbial, and genetic findings in 39 Colombian patients. [PDF]

J Hum Immun
Rojas J, Arango-Franco CA, Moncada-Velez M, Arboleda DM, Figueredo EA, Molina M, Sánchez JP, Zapata LM, Diaz PC, Álvarez JA, Serna-Arbelaez MS, Pérez Zapata LJ, Vélez G, Soudée C, Alzate JF, Cabarcas F, Obando Gil C, Garcés C, Alvarez-Olmos MI, Pérez-Camacho PM, Medina-Valencia D, Patiño-Niño JA, Rendón JP, Ortega-López MC, Cano LE, López JF, Estupiñán FM, Chaparro M, Niño L, Escobar AF, Casanova JL, Boisson-Dupuis S, Puel A, Olmos C, Sosa LM, Sarmiento-Wilches PE, Muñoz C, Orrego JC, López JÁ, Olaya-Hernández M, Builes N, Vásquez-Echeverri E, Vélez-Tirado N, Franco JL, Castaño-Jaramillo LM, Bustamante J, Arias AA.   +46 more
europepmc   +1 more source

Lupus Panniculitis Immunoprofiling Reveals a Cytotoxic, Type 1‐Skewed T‐Cell Response With Signs of Metabolic Alteration

Allergy, EarlyView.
Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri, Reihane Ziadlou, Stephan Traidl, Milena Sokolowska, Emmanuel Contassot, Nick Li, Maija Kiuru, Isabel Kolm, Werner Kempf, Emanual Maverakis, Cezmi Akdis, Marie‐Charlotte Brüggen   +11 more
wiley   +1 more source

Case Report: Invasive pulmonary aspergillosis caused by <i>Aspergillus lentulus</i> in a boy with chronic granulomatous disease. [PDF]

Front Med (Lausanne)
Tan S, Liao Q, Wen Y, Zhu Y.
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients. [PDF]

J Gene Med
da Rosa LM, da Rosa MB, Wilson MSLJ, Schwartz IVD, Sperb-Ludwig F.   +4 more
europepmc   +1 more source

Efficacy and safety of topical macrolides versus systemic tetracyclines for meibomian gland dysfunction–a systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To review the efficacy and safety of oral doxycycline antibiotics versus topical macrolides in the treatment of meibomian gland dysfunction (MGD). Design Systematic review and meta‐analysis. Methods A comprehensive search of PubMed, Scopus, Embase, and ClinicalTrials.gov through December 2024 identified randomised controlled trials ...
Margarita Safir, Clara C. Chan, Joshua C. Teichman, Itamar Arbel, Ruth Lapid‐Gortzak, Camiel J. F. Boon, Michael Mimouni, Dror Ben Ephraim Noyman   +7 more
wiley   +1 more source

Atopy and immune dysregulation among patients with chronic granulomatous disease. [PDF]

Front Immunol
Eisen S, Nagler-Bunker S, Leon-Ponte M, Chopra Y, Upton J, Kim VH, Grunebaum E.   +6 more
europepmc   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Case report: a case of CYBB gene variant in X-linked chronic granulomatous disease. [PDF]

BMC Pediatr
Lv H, Zhang J, Zhang Y, Wei G, Chen Y.
europepmc   +1 more source