Efficacy and Tolerability of Methotrexate for Idiopathic Granulomatous Mastitis: A Systematic Review and Meta-Analysis. [PDF]
Background Idiopathic granulomatous mastitis (IGM) is a challenging inflammatory breast disease with limited standardized treatment guidelines. Methods This meta‐analysis systematically evaluated the efficacy and safety of methotrexate (MTX) in IGM, pooling data from observational studies.
Han Y, Shi L, Zhang Y.
europepmc +2 more sources
Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long-Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report. [PDF]
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Davoudi-Monfared E +5 more
europepmc +2 more sources
Characterization of Novel MRI Findings in Idiopathic Granulomatous Mastitis: Diagnostic Significance and Clinical Perspectives. [PDF]
Objectives Idiopathic granulomatous mastitis (IGM) is an uncommon, benign, chronic inflammatory breast disease that frequently mimics carcinoma both clinically and radiologically, posing diagnostic challenges. While classical imaging manifestations have been described, the full spectrum of MRI features remains incompletely characterized.
Işık F, Öztürk ME, Alper F.
europepmc +2 more sources
Granulomatous mastitis - Case report. [PDF]
ABSTRACT Introduction and importance: Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory breast disease with unclear etiology and no standardized treatment. It often presents as a painful breast mass that mimics breast cancer, necessitating thorough diagnostic ...
Ribeiro CG +4 more
europepmc +3 more sources
Treatment Outcomes of Lobular Granulomatous Mastitis: Impact of Hyperprolactinemia, Diabetes, and Erythema Nodosum-Insights From a 7-Year Cohort Study. [PDF]
Background This study presents our observations on the management and follow‐up of patients diagnosed with lobular granulomatous mastitis (LGM) in a cohort study. Additionally, characteristics associated with a longer disease course, as well as treatment challenges in patients with erythema nodosum, diabetes, and hyperprolactinemia, would be discussed.
AkbariRad M +7 more
europepmc +2 more sources
Granulomatous mastitis (GM) is a quite rare inflammatory condition of the breast with varying clinical presentations and microbiological findings. Having excluded specific diseases connected with GM, a group of idiopathic GM (IGM) remains including a special form presenting with multiple small cysts named cystic neutrophil GM (CNGM).
Fatma Kesmez Can +2 more
openaire +5 more sources
Granulomatous lobular mastitis
AbstractGranulomatous lobular mastitis is an unusual breast benign inflammatory disorder with unknown aetiology. It is generally emerged with the clinical symptoms of breast mass, abscess, inflammation and mammary duct fistula. The diagnosis is made by histopathology with a chronic non‐necrotizing granulomatous inflammation in lobules of the breast ...
Fei Zhou +3 more
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Idiopathic granulomatous mastitis
To discuss the clinical and radiological features and treatment approaches in 14 patients diagnosed with idiopathic granulomatous mastitis (GM).We retrospectively evaluated the clinical features, radiological findings, and treatment approaches in 14 patients with idiopathic GM in the General Surgery Department, Gulhane School of Medicine, Ankara ...
Tufan, Turgut +6 more
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Granulomatous mastitis: A case report
Idiopathic granulomatous mastitis is a rare chronic benign inflammatory mastopathy occurring mainly in young women. With a non-specific imagery, it is considered as a diagnosis by exclusion and has a challenging treatment. Histologically, it is characterized by the predominance of polynuclear neutrophils and the absence of caseous necrosis. The breast
Koudouhonon Rita Oze +5 more
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Granulomatous Mastitis: A Spectrum of Disease [PDF]
SUMMARY: BACKGROUND: Granulomatous disease within the breast can result from a variety of causes. PATIENTS AND METHODS: We present 3 cases of this condition with 3 different underlying diagnoses. RESULTS: Each case was initially labelled as idiopathic granulomatous mastitis, although this was proven not to be correct on further investigation ...
Ragu, Vinayagam +2 more
openaire +2 more sources

