Results 231 to 240 of about 3,533,009 (320)
GNODEVAE: a graph-based ODE-VAE enhances clustering for single-cell data. [PDF]
Fu Z, Chen C, Wang S, Wang J, Chen S.
europepmc +1 more source
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Capturing trial-by-trial variability in behaviour: people with Parkinson's disease exhibit a greater rate of short-term fluctuations in response times. [PDF]
MacDonald HJ+3 more
europepmc +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
Good versus optimal: Why network analytic methods need more systematic evaluation
Zweig Katharina
doaj +1 more source
Cycle-configuration descriptors: a novel graph-theoretic approach to enhancing molecular inference. [PDF]
Song B+5 more
europepmc +1 more source
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
Computations in living organisms modeled by marked graphs. [PDF]
Myers JM, Madjid H.
europepmc +1 more source