Results 151 to 160 of about 142,988 (312)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Grappa: A GRAPh PAckage in JAVA

open access: yes, 1998
Grappa is an extensible graph drawing package written in Java. The package comprises classes that implement graph representation, presentation and layout services.
Lee, Wenke   +2 more
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

On graph classes with minor-universal elements

open access: yes, 2022
A graph $U$ is universal for a graph class $\mathcal{C}\ni U$, if every $G\in \mathcal{C}$ is a minor of $U$. We prove the existence or absence of universal graphs in several natural graph classes, including graphs component-wise embeddable into a ...
Georgakopoulos, Agelos
core  

Classes of bipartite graphs related to chordal graphs

open access: yesDiscrete Applied Mathematics, 1991
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

On stochastic completeness of weighted graphs

open access: yes, 2011
Huang X. On stochastic completeness of weighted graphs. Bielefeld: Universität; 2011.In this thesis we are concerned with the long time behavior of continuous time random walks on infinite graphs. The following three related problems are considered.
Huang, Xueping
core  

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

Connectivity of addable graph classes

open access: yes, 2007
A non-empty class A of labeled graphs is weakly addable if for each graph G∈A and any two distinct components of G, any graph that can be obtained by adding an edge between the two components is also in A.
Béla Bollobás   +5 more
core   +1 more source

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