Results 111 to 120 of about 1,256,700 (250)

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin   +8 more
wiley   +1 more source

Graph-based clustering and ranking for diversified image search

open access: yes, 2014
© 2014, Springer-Verlag Berlin Heidelberg. In this paper, we consider the problem of clustering and re-ranking web image search results so as to improve diversity at high ranks. We propose a novel ranking framework, namely cluster-constrained conditional
Liu, G   +9 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno   +19 more
wiley   +1 more source

Fast Spectral Clustering with efficient large graph construction

open access: yes, 2017
Spectral clustering has been regarded as a powerful tool for unsupervised tasks despite its excellent performance, the high computational cost has become a bottleneck which limits its application for large scale problems. Recent studies on anchor-based
Feiping Nie   +5 more
core   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Data Clustering by Laplacian Regularized L1-Graph

open access: yes, 2014
L1-Graph has been proven to be effective in data clustering, which partitions the data space by using the sparse representation of the data as the similarity measure.
Yang, Yingzhen   +11 more
core   +1 more source

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi   +27 more
wiley   +1 more source

Diverse representation-guided graph learning for multi-view metric clustering

open access: yesJournal of King Saud University: Computer and Information Sciences
Multi-view graph clustering has garnered tremendous interest for its capability to effectively segregate data by harnessing information from multiple graphs representing distinct views.
Xiaoshuang Sang   +3 more
doaj   +1 more source

Generative AI in clinical practice: how should rheumatologists evaluate and monitor emerging tools?

open access: yesArthritis Care &Research, Accepted Article.
Generative artificial intelligence (AI) is increasingly being used in rheumatology practice, to assist with tasks such as documentation, record summarization, and clinical decision support. Rheumatologists need a practical approach to determining what evidence and oversight each application requires.
Koushan Kouranloo   +2 more
wiley   +1 more source

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