Results 141 to 150 of about 178,314 (358)

Coping with new Challenges in Clustering and Biomedical Imaging

open access: yes, 2011
The last years have seen a tremendous increase of data acquisition in different scientific fields such as molecular biology, bioinformatics or biomedicine.
Oswald, Annahita
core  

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Unsupervised shape clustering using diffusion map [PDF]

open access: yes, 2008
The quotient space of all smooth and connected curves represented by a fixed number of boundary points is a finite-dimensional Riemannian manifold, also known as a shape manifold.
Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Graph Clustering Using Multiway Ratio Cut (Software Demonstration)

open access: yes, 1998
Identifying the natural clusters of nodes in a graph and treating them as supernodes or metanodes for a higher level graph (on an abstract graph) is a technique used for the reduction of visual complexity of graphs with a large number of nodes.
Roxborough, Tom, Sen, Arunabha
core   +1 more source

Building clustering method that integrates graph attention networks and spectral clustering

open access: yesGeocarto International
Clustering is an unsupervised learning method; however, it cannot be directly applied to complex building features to reveal the deep-level intrinsic relationships between buildings and assimilate the cartographic experience of experts.
Guoqing Chen, Haizhong Qian
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

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