Results 291 to 300 of about 2,245,805 (347)

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories. [PDF]

Nat Methods
Cheng M, Jansen J, Reimer KC, Grande VP, Nagai JS, Li Z, Kießling P, Grasshoff M, Kuppe C, Schaub MT, Kramann R, Costa IG.   +11 more
europepmc   +1 more source

A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy

Advanced Science, EarlyView.
The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling, Yixin Zhu, Min Li, Zongliang Xie, Lei Cao, Wentao Song, Dandan Wang, Duo Mao, Xiaonan Wang, Bin Liu   +9 more
wiley   +1 more source

Burden of colorectal cancer attributable to dietary risks in China from 1990 to 2021: findings from the Global Burden of Disease Study 2021. [PDF]

Front Nutr
Chen B, Zheng H, Huang R, Yu J, Wang X, Yang C, Guo Z, Zhan Z.   +7 more
europepmc   +1 more source

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

Advanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil, Jie Tian, Kun Jiang, Clarissa Westover, Sri Vaishnavi Thummalapalli, Arunachalam Ramanathan, Arpita Shome, Natalie Crutchfield, M. Taylor Sobczak, Sean Lee, Hongyue Sun, Elizabeth J. Brisbois, Hitesh Handa, Timothy E. Long, Xianqiao Wang, Kenan Song   +15 more
wiley   +1 more source

Forecasting global monthly cotton prices: the superiority of NNAR models over traditional models. [PDF]

Front Artif Intell
Limbu Sanwa R, Khadka R, Chi YN.
europepmc   +1 more source

Decision Revise: Measuring changes in polarisation using Singular Value Decomposition of network graphs. Round#3

Mario Angst
openalex   +1 more source

The principles behind equivariant neural networks for physics and chemistry. [PDF]

Proc Natl Acad Sci U S A
Kondor R.
europepmc   +1 more source

Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations. [PDF]

Front Microbiol
Hu S, Wang BT, Li T, Bu S, Jin CZ, Jin L, Ruan HH, Shin KS, Jin FJ.   +8 more
europepmc   +1 more source