Results 131 to 140 of about 1,795,811 (300)

Graph Pattern Matching: From Intractable to Polynomial Time [PDF]

open access: yes, 2010
Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong   +5 more
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Tits alternatives for graph products

open access: yes, 2015
We discuss various types of Tits Alternative for subgroups of graph products of groups, and prove that, under some natural conditions, a graph product of groups satisfies a given form of Tits Alternative if and only if each vertex group satisfies this ...
Antolin, Yago, Minasyan, Ashot
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Global stability for McKean–Vlasov equations on large networks

open access: yesEuropean Journal of Applied Mathematics
We investigate the mean-field dynamics of stochastic McKean differential equations with heterogeneous particle interactions described by large network structures.
Christian Kuehn, Tobias Wöhrer
doaj   +1 more source

Distributed Graph Simulation: Impossibility and Possibility [PDF]

open access: yes, 2014
This paper studies fundamental problems for distributed graph simulation. Given a pattern query Q and a graph G that is fragmented and distributed, a graph simulation algorithm A is to compute the matches Q(G) of Q in G.
Wang, Xin   +3 more
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

On the Laplacian index of tadpole graphs

open access: yesSpecial Matrices
In this article, we study the Laplacian index of tadpole graphs, which are unicyclic graphs formed by adding an edge between a cycle Ck{C}_{k} and a path Pn{P}_{n}.
Braga Rodrigo O., Veloso Bruno S.
doaj   +1 more source

Physics-Informed Graph Neural Network for Flight Dynamics Modeling

open access: yesAerospace
Flight dynamics modeling is a fundamental cornerstone of aircraft design, simulation, and control. Traditional approaches rely on aerodynamic look-up tables for numerical integration, which suffer from high data-acquisition costs, poor extrapolation ...
Liang Ma   +4 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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