Results 121 to 130 of about 1,423,064 (275)

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Doppler Shift Estimation Method for Frequency Diverse Array Radar Based on Graph Signal Processing

Remote Sensing
In this paper, a novel Doppler shift estimation method for frequency diverse array (FDA) radar based on graph signal processing (GSP) theory is proposed and investigated. First, a well-designed graph signal model for a monostatic linear FDA is formulated.
Ningbo Xie, Haijun Wang, Kefei Liao, Shan Ouyang, Hanbo Chen, Qinlin Li   +5 more
doaj   +1 more source

Reliability and limitations of Impact-Echo Method for Thickness Measurement of Orthotropic Composite Plates [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2018
In this paper, an Impact-Echo method has been used to numerically simulate low velocity impact of a steel ball on laminated composite plates in order to measure the plate's thickness.
M. Amiri, M. Tabatabaee Ghomi, Gh. Liaghat   +2 more
doaj  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

2 kWatt Harmonic Analyzer Prototype Using Discrete Fourier Transform Method [PDF]

, 2011
We knew that there are so many power harmonic analyzer in the market. Much of them are from well known company and commercialize that bring the engineer found it easily.
Hidayat, Wahyu, Puspita, Eru, Gunawan, Agus   +2 more
core  

Unifying Composition and Process Design: A Heterogeneous Graph Neural Network for Discovering High‐Performance Cu Alloys

Advanced Science, EarlyView.
By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin, Qian Lei, Wei Yan, Yue Li, Tong Xie, Shuang Zhou, Chong Wang, Bram Hoex, Qiang Long, Caoyang Jiang, Min Song, Zhou Li, Zhangwei Wang   +12 more
wiley   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Synergistic Integration of Artificial Merkel Disc and Meissner Corpuscle via Dermal Papillary Structures for Mechanically Filtered Multimodal Tactile Sensing

Advanced Science, EarlyView.
A multimodal tactile sensor module that mimics the spatial arrangement and function of Merkel discs and Meissner corpuscles within the human papillary structure operates in a self‐powered manner, responding to both dynamic and static stimuli, achieving tactile perception more similar to human skin.
Jaehyeong Kim, Bohee Maeng, Seunghwan Seo, Kyoung‐Yong Chun, Chang‐Soo Han   +4 more
wiley   +1 more source

Exceptional CO2 Hydrogenation to Gasoline Enabled by GaZrOx/Ga‐ZSM‐5 Tandem Catalyst

Advanced Science, EarlyView.
A GaZrOx/Ga‐ZSM‐5 tandem catalyst achieves 17.2% CO2 conversion with 83.2% C5+ selectivity and >400 h stability relies on optimized O‐vacancies and Ga‐H coverage for CO2 hydrogenation. ABSTRACT CO2 hydrogenation to gasoline offers a promising route for addressing energy challenges and enabling the effective utilization of carbon resources. However, the
Wenhui Li, Yujing Sun, Bingyu Liu, Yaoyang Ni, Hong Yang, Xinwen Guo   +5 more
wiley   +1 more source

Real‐Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch‐Induced Phase Separation

Advanced Science, EarlyView.
Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh, Akihide Sugawara, Naoaki Ishihara, Takashi Konishi, Yuki Ueda, Ryuhei Motokawa, Yoshinori Takashima, Hiroshi Uyama   +7 more
wiley   +1 more source