Results 231 to 240 of about 1,423,064 (275)

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source

Elliptic Fourier analysis as a tool for the taxonomic identification of isolated theropod pedal phalanges

The Anatomical Record, EarlyView.
Abstract Studies of Upper Cretaceous deposits in North America have provided invaluable insights into the continental ecosystems of this time. Theropod (Saurischia, Dinosauria) pedal phalanges are commonplace in these deposits but can be difficult to identify at a finer taxonomic resolution.
Trystan M. Warnock‐Juteau, Stephanie M. Smith, Thomas M. Cullen   +2 more
wiley   +1 more source

Global Results for Weakly Dispersive KP-II Equations on the Cylinder. [PDF]

Arch Ration Mech Anal
Herr S, Schippa R, Tzvetkov N.
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Evaluating BOLD functional MRI biophysical simulation approaches: Impact of vascular geometry, magnetic field calculations, and water diffusion models. [PDF]

Imaging Neurosci (Camb)
Berman AJL, Chaussé J, Hartung G, Polimeni JR, Chen JJ.   +4 more
europepmc   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

ERG-Graph: Graph Signal Processing of the Electroretinogram for Classification of Neurodevelopmental Disorders. [PDF]

Bioengineering (Basel)
Mercado-Diaz LR, Pinzon-Arenas JO, Constable PA, Lee IO, Loh L, Thompson DA, Posada-Quintero HF.   +6 more
europepmc   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

<i>Spatholobus suberectus</i> Stem-Derived Extracellular Vesicle-Like Particles Attenuate Glucocorticoid-Induced Osteoporosis via NRF2/HO-1 Signaling. [PDF]

Int J Nanomedicine
Chen G, Li H, Chen R, Yao Y, Lian G, Bai L, Chen H, Zhang C, Chen G.   +8 more
europepmc   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

BMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu, Yongsheng Zhou, Longwei Lv   +8 more
wiley   +1 more source