Results 81 to 90 of about 280,140 (285)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

On Lh,k-Labeling Index of Inverse Graphs Associated with Finite Cyclic Groups

Journal of Mathematics, 2021
An Lh,k-labeling of a graph G=V,E is a function f:V⟶0,∞ such that the positive difference between labels of the neighbouring vertices is at least h and the positive difference between the vertices separated by a distance 2 is at least k.
K. Mageshwaran, G. Kalaimurugan, Bussakorn Hammachukiattikul, Vediyappan Govindan, Ismail Naci Cangul   +4 more
doaj   +1 more source

Topological Integer Additive Set-Sequential Graphs

, 2015
Let $\mathbb{N}_0$ denote the set of all non-negative integers and $X$ be any non-empty subset of $\mathbb{N}_0$. Denote the power set of $X$ by $\mathcal{P}(X)$. An integer additive set-labeling (IASL) of a graph $G$ is an injective set-valued function $
Augustine, Germina, Sudev, Chithra, Sudev, Naduvath   +2 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Heinz Quarter Mean Labeling of Graphs

Ratio Mathematica
Mean labeling is one of the best-known labeling methods for graphs. Despite the large number of papers published on the subject of graph labeling, there are some particular formulas to be used by researchers to mean-label graphs.
Latha S, Sandhya SS
doaj   +1 more source

Novel Properties of Fuzzy Labeling Graphs

Journal of Mathematics, 2014
The concepts of fuzzy labeling and fuzzy magic labeling graph are introduced. Fuzzy magic labeling for some graphs like path, cycle, and star graph is defined. It is proved that every fuzzy magic graph is a fuzzy labeling graph, but the converse is not
A. Nagoor Gani, Muhammad Akram, D. Rajalaxmi (a) Subahashini   +2 more
doaj   +1 more source

Enumeration Of Labelled Graphs [PDF]

Canadian Journal of Mathematics, 1956
1. Introduction. The number of connected linear graphs having V vertices labelled 1, … , V and λ (unlabelled) lines is found below. Similar formulas are found for graphs in which slings, lines “in parallel,” or both are allowed and for directed graphs with or without slings or parallel lines.
openaire   +2 more sources

On Universal Cycles of Labeled Graphs [PDF]

The Electronic Journal of Combinatorics, 2010
A universal cycle is a compact listing of a class of combinatorial objects. In this paper, we prove the existence of universal cycles of classes of labeled graphs, including simple graphs, trees, graphs with $m$ edges, graphs with loops, graphs with multiple edges (with up to $m$ duplications of each edge), directed graphs, hypergraphs, and $k ...
Greg Brockman, Bill Kay, Emma E. Snively
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

α_{2}-labeling of graphs [PDF]

Opuscula Mathematica, 2009
We show that if a graph \(G\) on \(n\) edges allows certain special type of rosy labeling (a.k.a. \(\rho\)-labeling), called \(\alpha_2\)-labeling, then for any positive integer \(k\) the complete graph \(K_{2nk+1}\) can be decomposed into copies of \(G\)
Dalibor Fronček
doaj   +1 more source